No spam. Unsubscribe anytime.
Batch purity, right where researchers look for it.
Each included compound carries its own HPLC result, batch reference, and testing date so the research brief is backed by real analytical proof.
Semax
Purity (HPLC)
Selank
Purity (HPLC)
Dihexa
Purity (HPLC)
Nootropic Pathway Study Kit
Three compounds covering different parts of the cognitive literature
A three-compound cognitive kit organized around attention, stress-response, and synaptic-plasticity research.
Research Use Only. These kits are intended for laboratory research purposes only. Not for human consumption. Public-page summaries reflect published literature and analytical documentation, not human-use instructions or treatment claims.
Built from published research, not guesswork.
Every public research kit now leads with the proof: cited studies, PMIDs, tracked signals, and batch-level documentation across each component.
Common measurements, markers, and readouts associated with this research lane in published literature.
What is inside the kit, structurally
Core chemistry details pulled from each included compound so the page feels like a real research profile, not a generic bundle card.
Semax
CAS: 80714-61-0Semax is a synthetic heptapeptide analog of ACTH(4-10) with a stabilizing Pro-Gly-Pro extension. It increases BDNF and TrkB receptor expression, enhances neurotrophic factor signaling, modulates dopaminergic and serotonergic neurotransmission, and provides neuroprotection through antioxidant and inflammatory-pathway mechanisms. Unlike ACTH, Semax has no steroidogenic activity. It improves cerebral circulation, enhances memory consolidation, and has been approved in Russia and Ukraine for stroke recovery and cognitive enhancement.
Selank
CAS: 129954-34-3Selank is a synthetic heptapeptide derived from the immunomodulatory peptide tuftsin (Thr-Lys-Pro-Arg) with a C-terminal Pro-Gly-Pro extension that enhances metabolic stability. It modulates the balance of Th1/Th2 cytokines, influences enkephalinase activity, and increases BDNF mRNA expression in the hippocampus. Selank produces anxiolytic effects comparable to benzodiazepines without sedation, cognitive impairment, or dependence by modulating GABAergic neurotransmission and monoamine metabolism in limbic structures.
Dihexa
CAS: 1401708-83-5Dihexa is a small, orally active, blood-brain barrier-permeable oligopeptide derivative of angiotensin IV. It acts as an allosteric agonist of the hepatocyte growth factor (HGF)/c-Met receptor system, potentiating HGF signaling at picomolar concentrations. This drives neurogenesis, synaptogenesis, and spinogenesis in the hippocampus. Dihexa is reportedly 10 million times more potent than BDNF in promoting neurite outgrowth. It also enhances synaptic plasticity and long-term potentiation, the cellular basis of learning and memory.
Published study parameters
Typical dose ranges, intervals, and administration routes cited in the literature for the compounds in this kit.
Semax and Selank are nasal peptides — no injection needed. Dihexa is administered subcutaneously. All three can be used simultaneously. Published protocols reference morning administration for Semax and Dihexa (focus-related outcomes); Selank is referenced in both morning and evening protocols.
Semax
MorningSelank
Morning or eveningDihexa
MorningThese are publication-style study parameters summarized from cited literature and investigational designs. They are provided as research context only, not as human-use instructions or recommendations.
Published Research
Featured peer-reviewed papers supporting the compounds and pairing logic in this kit.
Semax, an ACTH(4-10) analogue with nootropic properties, activates BDNF and trkB gene expression in the rat hippocampus
Dolotov OV, Karpenko EA, Inozemtseva LS, et al.
Published data demonstrated Semax produced significant upregulation of BDNF and TrkB receptor gene expression in hippocampal tissue, supporting neurotrophic mechanisms of cognitive enhancement.
PMID: 16386239
Selank administration affects the expression of some genes involved in GABAergic neurotransmission
Zozulya AA, Sizov ME, Tsvetkova IV, et al.
In peer-reviewed research, Selank demonstrated modulation of GABA-A receptor subunit gene expression, providing a molecular basis for its anxiolytic activity without sedative or tolerance-building effects.
PMID: 19145305
Dihexa, a small molecule analog of angiotensin IV, is a potent neurotrophic agent and synaptogenic compound
McCoy AT, Benoist CC, Wright JW, et al.
Literature demonstrates Dihexa was seven orders of magnitude more potent than BDNF at augmenting HGF/c-Met receptor signaling, promoting new synapse formation in published neuronal culture studies.
PMID: 23303219
Neuroprotective effects of Semax in conditions of global cerebral ischemia in rats
Bashkatova VG, Koshelev VB, Fadyukova OE, et al.
Published studies observed significant neuroprotective effects of Semax in ischemic models, with reduced neuronal damage and improved functional recovery markers in animal studies.
PMID: 11687856
What researchers commonly track
Common measurements, markers, and readouts associated with this research lane in published literature.
Observed in the literature
A plain-English view of how published study windows, markers, and reported changes tend to unfold across this research lane.
Neurotrophic Factor Initiation
BDNF Upregulation & Anxiolytic Consolidation
Synaptic Plasticity & Network Formation
Stress Resilience & Emotional Regulation
Cognitive Performance Consolidation
Protocol Completion & Sustained Neuroplasticity
Handling and documentation
Material handling details and batch-level documentation that support clean research workflows.
Water Volume
1 mL bacteriostatic water per 10mg vial (Semax/Selank for intranasal use)
Concentration
10 mg/mL — Semax/Selank: 200-600 mcg intranasal; Dihexa: consult published protocols
Storage
Refrigerate at 2-8°C after reconstitution. Semax/Selank stable 14 days. Dihexa stable 28 days. Do not freeze.
Why these compounds are paired in the literature
Plain-English summaries of the mechanisms and published pairings that make this kit coherent for real research work.
Published research shows Semax upregulates BDNF (brain-derived neurotrophic factor) expression, supporting neuroplasticity and synaptic formation in studied models (PMID: 17116167).
Studies indicate Selank modulates anxiolytic pathways without sedative effects, while also showing immunomodulatory activity as a secondary mechanism (PMID: 18577767).
Dihexa has been shown in published research to be a potent hepatocyte growth factor modulator, enhancing synaptic connectivity and demonstrating significant effects on memory-related pathways (PMID: 23530037).
What's in This Kit
3 peptides, each with individual COA documentation
Semax
$37.95Cognitive enhancement and memory consolidation · Stroke recovery and neuroprotection · BDNF and neurotrophin pathway upregulation
Semax is a synthetic heptapeptide analog of ACTH(4-10) with a stabilizing Pro-Gly-Pro extension.
Selank
$32.95Anxiety reduction without sedation · Immune modulation via tuftsin pathway · Cognitive enhancement and memory
Selank is a synthetic heptapeptide derived from the immunomodulatory peptide tuftsin (Thr-Lys-Pro-Arg) with a C-terminal Pro-Gly-Pro extension that enhances metabolic stability.
Dihexa
$60.00Cognitive enhancement (claimed as most potent nootropic) · HGF/c-Met receptor biology · Alzheimer's and dementia research
Dihexa is a small, orally active, blood-brain barrier-permeable oligopeptide derivative of angiotensin IV.
Go deeper on the peptides inside the kit
Article picks tied directly to the compounds in this kit, so researchers can move from the bundle view into peptide-specific literature, mechanism, and handling context.
Dihexa: The Potent Nootropic Peptide
Comprehensive guide to dihexa including mechanism of action, published studies, and practical research information.
Cognitive & Nootropic Peptides: Research Guide
Nootropic market is huge. Pillar content for cognitive category. Comprehensive research guide covering mechanism of action, published studies, and.
Selank vs Semax vs Dihexa: Nootropics
Nootropic community loves comparisons. Good engagement content. Comprehensive research guide covering mechanism of action, published studies, and.
Nootropic Peptide Stack: Research Protocol
Nootropic stacking is heavily searched. Promotes multiple products. Comprehensive research guide covering mechanism of action, published studies, and.
Peptides for Neurodegeneration
Growing research area. Appeals to academic audience. Comprehensive research guide covering mechanism of action, published studies, and practical.
Selank and Semax: Nootropic Peptides
Review of selank and semax, two synthetic neuropeptides for cognitive enhancement and neuroprotection research.
Related Research Kits
Delta Sleep Architecture Kit
Delta-wave sleep patterns, tissue repair, and anxiolytic GABA-pathway compounds studied in published literature
3 peptides · Neuroscience
Tissue Repair Research Kit
The two most-cited tissue repair peptides studied together in published literature
2 peptides · Tissue Research
Incretin Pathway Comparator Kit
Single vs. dual receptor activation — the compounds from the STEP and SURPASS trials
2 peptides · Metabolic Research
Start Your Research
Get the complete Nootropic Pathway Study Kit at $115.19 — save $15.71 versus purchasing each compound separately. Full COA documentation included with every vial.
Research Use Only. These kits are intended for laboratory research purposes only. Not for human consumption. Public-page summaries reflect published literature and analytical documentation, not human-use instructions or treatment claims.