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HPLC Purity Analysis
GDF-8
CAS: Not formally assigned for recombinant research peptide
muscle-signaling regulation and hypertrophy · Muscular dystrophy and muscle wasting research · Myostatin inhibitor development (drug target)
Myostatin (GDF-8) is a secreted TGF-beta superfamily member that serves as the principal negative regulator of skeletal muscle mass.
- muscle-signaling regulation and hypertrophy
- Muscular dystrophy and muscle wasting research
- Myostatin inhibitor development (drug target)
- TGF-beta superfamily signaling
This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.
Frequently Bought Together
Bacteriostatic Water
Required for reconstitution
AICAR
Specialty / Research
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HPLC Purity Analysis
Specifications
How GDF-8 Works
Myostatin (GDF-8) is a secreted TGF-beta superfamily member that serves as the principal negative regulator of skeletal muscle mass. It signals through activin type IIB receptors (ActRIIB) and type I receptors (ALK4/ALK5), activating Smad2/3 transcription factors that suppress myogenic gene expression (MyoD, myogenin) and inhibit satellite cell activation, myoblast proliferation, and differentiation. Myostatin loss-of-function mutations produce dramatic muscle hypertrophy in multiple species. The propeptide remains associated with mature myostatin as an inhibitor until cleaved by BMP-1/tolloid proteases.
Research Applications
Pricing
| Size | Per Vial | 10-Pack |
|---|---|---|
1mg | $140.00 | $1400.00 |
10-pack pricing shown. Volume discounts for 50+ vials — contact us.
Certificate of Analysis
This COA is a representative sample. A batch-specific Certificate of Analysis with full HPLC chromatograms and mass spectrometry data is included with every order.
Research Use Only. This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.
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