ARA290 (Cibinetide) - Front - MiPeptidos
Specialty / Research

ARA290 (Cibinetide)

CAS: 1208243-50-8

ARA290 (Cibinetide) is a research peptide in the specialty / research category. ARA-290 is a synthetic 11-mer peptide that selectively activates the innate repair receptor (IRR), a heterodimer of the erythropoietin receptor (EPOR) and the beta common receptor (betacR/CD131). MiPeptidos offers ARA290 (Cibinetide) in 2 sizes with 99.8% verified purity and full analytical documentation.

Starting at
$28.95/vial
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≥99% Purity
COA Included
Third-Party Tested
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CoA Included
HPLC Verified
GMP Compliant
Third-Party Tested
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Batch Tracked

How ARA290 (Cibinetide) Works

ARA-290 is a synthetic 11-mer peptide that selectively activates the innate repair receptor (IRR), a heterodimer of the erythropoietin receptor (EPOR) and the beta common receptor (betacR/CD131). Unlike EPO, ARA-290 does not stimulate erythropoiesis or increase red blood cell production. Instead, it activates tissue-protective and anti-inflammatory signaling cascades including JAK2/STAT3, PI3K/Akt, and MAPK pathways. This provides neuroprotection, anti-inflammatory effects, and tissue repair without the thrombotic risks of EPO.

Research Applications

1
Neuropathic pain (sarcoidosis-related small fiber neuropathy)
2
Innate repair receptor pharmacology
3
Non-erythropoietic tissue protection
4
Diabetic neuropathy
5
Anti-inflammatory peptide therapeutics
View Published Research on PubMed →

Pricing

SizePer Vial10-Pack
10mg
$28.95$210.95
16mgBest Value
$39.95$291.95

Prices shown per vial from 10-pack. Volume discounts available for 50+ vials — contact us.

HPLC Purity Analysis

High-Performance Liquid Chromatography
99.8%purity
mAURetention Time (min)0250500750100005101520253099.8%
Method: RP-HPLC C18 ColumnDetection: UV 220nmMobile Phase: Acetonitrile/Water + 0.1% TFA

Certificate of Analysis

MiPeptidos
ARA290 (Cibinetide)
PASSES ALL SPECIFICATIONS
Batch NumberHR-R290-2600115
Date of AnalysisJanuary 4, 2026
Purity (HPLC)99.8%
AppearanceWhite to off-white lyophilized powder
SolubilityFreely soluble in sterile water and bacteriostatic water
Molecular Weight (MS)1257.30 Da — Confirmed
Endotoxin (LAL)<0.1 EU/mg
Sterility (USP <71>)Passes USP <71>

This COA is a representative sample. A batch-specific Certificate of Analysis with full HPLC chromatograms and mass spectrometry data is included with every MiPeptidos order.

Reconstitution Calculator

Add this much bacteriostatic water:
10.0 mL
10 mg ARA290 (Cibinetide) + 10.0 mL BAC water = 1 mg/mL

Inject bacteriostatic water slowly along the vial wall. Gently swirl until dissolved — never shake. Store reconstituted solution at 2-8°C and use within 30 days.

Download Product Brochure

Get our detailed ARA290 (Cibinetide) product brochure with specifications, research applications, HPLC analysis data, and reconstitution guide. Available in English and Spanish.

Customer Reviews

5.0/5from 1 review
Verified
Dr. Hans Weber·Zurich, Switzerland

ARA-290 is a non-erythropoietic EPO-derived peptide essential for our tissue-protective receptor studies. MiPeptidos' 11-amino-acid helix B surface peptide shows innate repair receptor activation without erythropoietic s...

Dec 28, 2025
View All Reviews →

Frequently Asked Questions

ARA290 (Cibinetide) (CAS: 1208243-50-8) is a research compound, with a molecular weight of 1257.30 Da in the Specialty / Research category. ARA-290 is a synthetic 11-mer peptide that selectively activates the innate repair receptor (IRR), a heterodimer of the erythropoietin receptor (EPOR) and the beta common receptor (betacR/CD131). Unlike EPO, ARA-290 does not stimulate erythropoiesis or increase red blood cell production. Researchers commonly investigate ARA290 (Cibinetide) for Neuropathic pain (sarcoidosis-related small fiber neuropathy), Innate repair receptor pharmacology, Non-erythropoietic tissue protection. Every vial from MiPeptidos includes batch-specific analytical documentation.
ARA290 (Cibinetide) is available in 2 sizes (10mg, 16mg), so reconstitution volume depends on which vial you have. For the 10mg size, add 2-3mL of bacteriostatic water; for the 16mg size, use 3-5mL. Always let the vial warm to room temperature first, inject the water slowly along the vial wall, and swirl gently — never shake. Store reconstituted ARA290 (Cibinetide) at 2-8°C and use within 30 days. MiPeptidos carries bacteriostatic water in 3mL and 10mL vials.
ARA-290 (Cibinetide, 1257 Da) is an 11-amino acid peptide derived from the tissue-protective domain of erythropoietin (EPO) that activates the innate repair receptor (EPOR/betacR heterodimer) WITHOUT stimulating erythropoiesis. Full EPO activates the classical EPOR homodimer for red blood cell production, which can cause dangerous polycythemia. ARA-290 provides tissue protection and nerve repair without hematological effects. MiPeptidos carries both for researchers studying EPO receptor subtypes.
Store lyophilized ARA290 (Cibinetide) at -20°C for maximum long-term stability — properly stored, it remains potent for 24+ months. Once reconstituted with bacteriostatic water, keep it refrigerated at 2-8°C and use within 30 days. In research applications, ARA290 (Cibinetide) has a reported half-life of ~5-10 minutes IV (rapid clearance; tissue-protective effects persist longer), which informs dosing frequency and protocol design. Avoid repeated freeze-thaw cycles and protect from direct light. MiPeptidos ships every order with cold-chain packaging to maintain integrity during transit.
Every ARA290 (Cibinetide) order from MiPeptidos includes a batch-specific Certificate of Analysis. Our current batch (HR-R290-2600115, tested January 4, 2026) shows 99.8% purity by HPLC, mass spectrometry confirmation at 1257.30 Da, endotoxin levels below 0.1 EU/mg, and passing sterility per USP <71>. This level of documentation ensures you can verify compound identity and purity before beginning your research. MiPeptidos also offers bulk pricing on orders of 50+ vials — contact info@mipeptidos.com.

Specifications

Purity
≥99%
Form
Lyophilized Powder
CAS Number
1208243-50-8
Mol. Weight
1257.30 Da
Formula
C51H84N16O21
Half-Life
~5-10 minutes IV (rapid clearance; tissue-protective effects persist longer)
Storage
Store at -20°C. Reconstituted: 2–8°C for up to 30 days.
Sizes
10mg, 16mg

Sequence

11-amino acid synthetic peptide designed to bind the tissue-protective receptor (innate repair receptor / EPO-betacR heterodimer)

Research Use Only. This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.

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