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HPLC Purity Analysis
ACE 031
CAS: 1169766-01-1
Duchenne muscular dystrophy (clinical trials conducted) · Myostatin inhibition and muscle-signaling · Muscle wasting and sarcopenia
ACE-031 is a soluble decoy receptor consisting of the extracellular domain of activin receptor type IIB (ActRIIB) fused to a human IgG1 Fc domain.
- Duchenne muscular dystrophy (clinical trials conducted)
- Myostatin inhibition and muscle-signaling
- Muscle wasting and sarcopenia
- TGF-beta superfamily ligand trap biology
This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.
Frequently Bought Together
Bacteriostatic Water
Required for reconstitution
AICAR
Specialty / Research
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HPLC Purity Analysis
Specifications
How ACE 031 Works
ACE-031 is a soluble decoy receptor consisting of the extracellular domain of activin receptor type IIB (ActRIIB) fused to a human IgG1 Fc domain. It functions as a ligand trap, binding and neutralizing myostatin (GDF-8), activin A, GDF-11, and other TGF-beta superfamily ligands that negatively regulate muscle-signaling. By sequestering these ligands in the circulation, ACE-031 removes the natural brake on muscle-signaling, resulting in significant increases in muscle mass and strength. The Fc domain provides extended half-life through FcRn recycling.
Research Applications
Pricing
| Size | Per Vial | 10-Pack |
|---|---|---|
1mg | $498.95 | $4989.50 |
10-pack pricing shown. Volume discounts for 50+ vials — contact us.
Certificate of Analysis
This COA is a representative sample. A batch-specific Certificate of Analysis with full HPLC chromatograms and mass spectrometry data is included with every order.
Research Use Only. This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.
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