FOXO4-DRI Brochure

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HPLC Purity Analysis

High-Performance Liquid Chromatography

99.7%purity

Method: RP-HPLC C18|UV 220nm|ACN/H₂O + 0.1% TFA

Anti-Aging / Longevity

FOXO4-DRI

Name: FOXO4-DRI
Brand: MiPeptidos
Availability: InStock

CAS: 2460055-10-9

Senescent cell clearance (senolytic therapy) · Aging reversal and rejuvenation · FOXO4/p53 interaction biology

FOXO4-DRI is a retro-inverso peptide (D-amino acid mirror image in reverse sequence) designed to disrupt the interaction between FOXO4 and p53 in senescent cells.

Senescent cell clearance (senolytic therapy)
Aging reversal and rejuvenation
FOXO4/p53 interaction biology
Age-related organ deterioration

Research Use Only.

This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.

Frequently Bought Together

Bacteriostatic Water

Required for reconstitution

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Epithalon

Anti-Aging / Longevity

$23.95

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$234.95/vial

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Vials1

Earn 2,350 pts —

✓ ≥99% HPLC|✓ COA Included|✓ Ships Today

≥99% Purity

COA Included

Third-Party Tested

Same-Day Shipping

FOXO4-DRI Brochure

Free download — PDF format

ProtocolsHPLC DataDosingEN + ES

No spam. Unsubscribe anytime.

HPLC Purity Analysis

High-Performance Liquid Chromatography

99.7%purity

Method: RP-HPLC C18|UV 220nm|ACN/H₂O + 0.1% TFA

CoA Included

|HPLC Verified

|GMP Compliant

|Third-Party Tested

|Same-Day Shipping

|Batch Tracked

Specifications

Purity

≥99%

Form

Lyophilized Powder

CAS

2460055-10-9

Mol. Weight

5358.05 Da

How FOXO4-DRI Works

FOXO4-DRI is a retro-inverso peptide (D-amino acid mirror image in reverse sequence) designed to disrupt the interaction between FOXO4 and p53 in senescent cells. In cellular senescence, FOXO4 accumulates in the nucleus and sequesters p53, preventing p53-mediated apoptosis and keeping senescent cells alive. FOXO4-DRI competitively blocks this interaction, freeing p53 to trigger apoptosis selectively in senescent cells while sparing healthy cells. This makes it a targeted senolytic agent.

Research Applications

Senescent cell clearance (senolytic therapy)

Aging reversal and rejuvenation

FOXO4/p53 interaction biology

Age-related organ deterioration

Retro-inverso peptide drug design

View Published Research on PubMed →

Pricing

Size	Per Vial	10-Pack
10mg	$234.95	$2349.50

10-pack pricing shown. Volume discounts for 50+ vials — contact us.

Certificate of Analysis

MiPeptidos

FOXO4-DRI

PASSES ALL SPECIFICATIONS

Batch NumberHR-FX4D-2600115

Date of AnalysisFebruary 19, 2026

Purity (HPLC)99.7%

AppearanceWhite to off-white lyophilized powder

SolubilityFreely soluble in sterile water and bacteriostatic water

Molecular Weight (MS)5358.05 Da — Confirmed

Endotoxin (LAL)<0.1 EU/mg

Sterility (USP <71>)Passes USP <71>

Download Full COA (PDF)

This COA is a representative sample. A batch-specific Certificate of Analysis with full HPLC chromatograms and mass spectrometry data is included with every order.

Research Use Only. This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.