Epithalon - Front - MiPeptidos
Anti-Aging / Longevity

Epithalon

CAS: 307297-39-8

Epithalon is a research peptide in the anti-aging / longevity category. Epithalon is a synthetic tetrapeptide based on the natural epithalamin produced by the pineal gland. MiPeptidos offers Epithalon in 2 sizes with 99.5% verified purity and full analytical documentation.

Starting at
$14.95/vial
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≥99% Purity
COA Included
Third-Party Tested
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CoA Included
HPLC Verified
GMP Compliant
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How Epithalon Works

Epithalon is a synthetic tetrapeptide based on the natural epithalamin produced by the pineal gland. It activates telomerase (hTERT), the enzyme responsible for adding telomeric repeats to chromosome ends, thereby extending telomere length and increasing cellular replicative capacity. It also stimulates melatonin production from the pineal gland, restoring circadian rhythm function that declines with age. Additionally, it modulates antioxidant enzyme expression and has been shown to extend lifespan in animal models.

Research Applications

1
Telomerase activation and telomere elongation
2
Anti-aging and lifespan extension
3
Circadian rhythm and melatonin restoration
4
Cancer prevention through telomere stabilization
5
Age-related gene expression modulation
View Published Research on PubMed →

Pricing

SizePer Vial10-Pack
10mg
$14.95$108.95
50mgBest Value
$58.95$429.95

Prices shown per vial from 10-pack. Volume discounts available for 50+ vials — contact us.

HPLC Purity Analysis

High-Performance Liquid Chromatography
99.5%purity
mAURetention Time (min)0250500750100005101520253099.5%
Method: RP-HPLC C18 ColumnDetection: UV 220nmMobile Phase: Acetonitrile/Water + 0.1% TFA

Certificate of Analysis

MiPeptidos
Epithalon
PASSES ALL SPECIFICATIONS
Batch NumberHR-PTHL-2600115
Date of AnalysisFebruary 1, 2026
Purity (HPLC)99.5%
AppearanceWhite to off-white lyophilized powder
SolubilityFreely soluble in sterile water and bacteriostatic water
Molecular Weight (MS)390.35 Da — Confirmed
Endotoxin (LAL)<0.1 EU/mg
Sterility (USP <71>)Passes USP <71>

This COA is a representative sample. A batch-specific Certificate of Analysis with full HPLC chromatograms and mass spectrometry data is included with every MiPeptidos order.

Reconstitution Calculator

Add this much bacteriostatic water:
10.0 mL
10 mg Epithalon + 10.0 mL BAC water = 1 mg/mL

Inject bacteriostatic water slowly along the vial wall. Gently swirl until dissolved — never shake. Store reconstituted solution at 2-8°C and use within 30 days.

Download Product Brochure

Get our detailed Epithalon product brochure with specifications, research applications, HPLC analysis data, and reconstitution guide. Available in English and Spanish.

Researcher Reviews

5.0/5from 1 review
Verified
Marina Volkov·St. Petersburg, Russia

Epithalon (epitalon) is central to our telomerase activation research. The Ala-Glu-Asp-Gly tetrapeptide from MiPeptidos showed clear telomerase upregulation in our human fibroblast cultures. At >99% purity for a four-res...

Jan 10, 2026
View All Reviews →

Frequently Asked Questions

Epithalon (CAS: 307297-39-8) is a research compound, with a molecular weight of 390.35 Da in the Anti-Aging / Longevity category. Epithalon is a synthetic tetrapeptide based on the natural epithalamin produced by the pineal gland. It activates telomerase (hTERT), the enzyme responsible for adding telomeric repeats to chromosome ends, thereby extending telomere length and increasing cellular replicative capacity. Researchers commonly investigate Epithalon for Telomerase activation and telomere elongation, Anti-aging and lifespan extension, Circadian rhythm and melatonin restoration. Every vial from MiPeptidos includes batch-specific analytical documentation.
Epithalon is available in 2 sizes (10mg, 50mg), so reconstitution volume depends on which vial you have. For the 10mg size, add 2-3mL of bacteriostatic water; for the 50mg size, use 5-6mL. Always let the vial warm to room temperature first, inject the water slowly along the vial wall, and swirl gently — never shake. Store reconstituted Epithalon at 2-8°C and use within 30 days. MiPeptidos carries bacteriostatic water in 3mL and 10mL vials.
Epithalon (Epitalon) and Pinealon are both short synthetic peptides from the Khavinson bioregulatory peptide family, but they target different aspects of aging. Epithalon (Ala-Glu-Asp-Gly, 390 Da) activates telomerase to lengthen telomeres, while Pinealon (Glu-Asp-Arg, 418 Da) is a neuroprotective tripeptide targeting pineal gland function. Epithalon has the strongest evidence for direct telomerase activation of any known peptide. MiPeptidos carries both for longevity and anti-aging research.
Store lyophilized Epithalon at -20°C for maximum long-term stability — properly stored, it remains potent for 24+ months. Once reconstituted with bacteriostatic water, keep it refrigerated at 2-8°C and use within 30 days. In research applications, Epithalon has a reported half-life of Short in plasma; biological effects (telomerase activation) persist for weeks, which informs dosing frequency and protocol design. Avoid repeated freeze-thaw cycles and protect from direct light. MiPeptidos ships every order with cold-chain packaging to maintain integrity during transit.
Every Epithalon order from MiPeptidos includes a batch-specific Certificate of Analysis. Our current batch (HR-PTHL-2600115, tested February 1, 2026) shows 99.5% purity by HPLC, mass spectrometry confirmation at 390.35 Da, endotoxin levels below 0.1 EU/mg, and passing sterility per USP <71>. This level of documentation ensures you can verify compound identity and purity before beginning your research. MiPeptidos also offers bulk pricing on orders of 50+ vials — contact info@mipeptidos.com.

Specifications

Purity
≥99%
Form
Lyophilized Powder
CAS Number
307297-39-8
Mol. Weight
390.35 Da
Formula
C14H22N4O9
Half-Life
Short in plasma; biological effects (telomerase activation) persist for weeks
Storage
Store at -20°C. Reconstituted: 2–8°C for up to 30 days.
Sizes
10mg, 50mg

Sequence

Ala-Glu-Asp-Gly (tetrapeptide)

Research Use Only. This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.

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