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HPLC Purity Analysis
5-AMINO-1MQ
CAS: 42464-96-0
NNMT inhibition and adipose tissue metabolism · NAD+ salvage pathway enhancement · energy-balance research treatment without appetite suppression
5-Amino-1MQ is a selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme highly expressed in adipose tissue that methylates and inactivates nicotinamide (a NAD+ precursor).
- NNMT inhibition and adipose tissue metabolism
- NAD+ salvage pathway enhancement
- energy-balance research treatment without appetite suppression
- Metabolic syndrome and insulin resistance
This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.
Frequently Bought Together
Bacteriostatic Water
Required for reconstitution
AICAR
Specialty / Research
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HPLC Purity Analysis
Specifications
How 5-AMINO-1MQ Works
5-Amino-1MQ is a selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme highly expressed in adipose tissue that methylates and inactivates nicotinamide (a NAD+ precursor). By inhibiting NNMT, 5-Amino-1MQ increases intracellular NAD+ and S-adenosylmethionine (SAM) levels, activating SIRT1 and other NAD+-dependent metabolic enzymes. This leads to increased energy expenditure, enhanced fatty acid oxidation, reduced lipogenesis, and decreased adipocyte size. It effectively reverses diet-induced energy-balance research in preclinical models without affecting food intake.
Research Applications
Pricing
| Size | Per Vial | 10-Pack |
|---|---|---|
5mg | $162.95 | $1629.50 |
10mgBest Value | $50.00 | $500.00 |
10-pack pricing shown. Volume discounts for 50+ vials — contact us.
Certificate of Analysis
This COA is a representative sample. A batch-specific Certificate of Analysis with full HPLC chromatograms and mass spectrometry data is included with every order.
Research Use Only. This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.
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