Delta Sleep Architecture Kit

DSIP is a nonapeptide originally isolated from rabbit cerebral venous blood during electrically induced sleep. It promotes delta-wave (slow-wave) sleep by modulating neuroendocrine signaling, although its exact receptor has not been definitively identified. DSIP modulates corticotropin and cortisol levels, influences the hypothalamic-pituitary-adrenal axis, has analgesic properties through opioid system modulation, and exhibits antioxidant effects. It normalizes disrupted sleep architecture and has stress-protective effects on multiple organ systems.

BPC-157 is a synthetic 15-amino acid fragment derived from human gastric body protection compound. It promotes angiogenesis by upregulating VEGF and its receptor VEGFR2, activates the FAK-paxillin pathway to enhance cell migration and wound closure, and modulates the nitric oxide system. It also interacts with the dopaminergic system and has cytoprotective effects on gastrointestinal mucosa, tendons, ligaments, and other connective tissues.

Selank is a synthetic heptapeptide derived from the immunomodulatory peptide tuftsin (Thr-Lys-Pro-Arg) with a C-terminal Pro-Gly-Pro extension that enhances metabolic stability. It modulates the balance of Th1/Th2 cytokines, influences enkephalinase activity, and increases BDNF mRNA expression in the hippocampus. Selank produces anxiolytic effects comparable to benzodiazepines without sedation, cognitive impairment, or dependence by modulating GABAergic neurotransmission and monoamine metabolism in limbic structures.