Folleto de SS-31

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Análisis de Pureza HPLC

Cromatografía Líquida de Alta Resolución

99.4%pureza

Method: RP-HPLC C18|UV 220nm|ACN/H₂O + 0.1% TFA

Antienvejecimiento / Longevidad

SS-31

Name: SS-31
Brand: MiPeptidos
Availability: InStock
Rating: 4.8 (111 reviews)

CAS: 736992-21-5

Estudiado para la estabilización de cardiolipina y reparación mitocondrial

SS-31 is a research peptide in the anti-aging / longevity category. SS-31 is a cell-permeable, mitochondria-targeted tetrapeptide that concentrates ~1000-fold in the inner mitochondrial membrane by binding to cardiolipin, a phospholipid unique to this membrane. MiPeptidos offers SS-31 in 2 sizes with 99.4% verified purity and full analytical documentation.

Restored cellular energy
Improved exercise capacity
Reduced oxidative damage
Heart and kidney support

Qué Esperar

Studies report improved energy and reduced fatigue within 3-5 days as SS-31 concentrates 1000x in mitochondrial membranes. By weeks 3-6, research suggests progressively better exercise capacity and recovery as the energy-producing machinery in your cells is structurally repaired. Full benefits typically emerge by weeks 7-10.

4.8(111 verified reviews)

RecomendadoSuscripción

Paquete de Protocolo de Investigación

$155.70

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Tu Protocolo de Investigación Incluye

6 × 10mg vials of SS-31

3 × Bacteriostatic Water (FREE)

12-week dosing research protocol

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$25.95/vial · Everything you need to start

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Folleto de SS-31

Descarga gratuita — formato PDF

ProtocolosDatos HPLCDosificaciónEN + ES

Sin spam. Cancela en cualquier momento.

Análisis de Pureza HPLC

Cromatografía Líquida de Alta Resolución

99.4%pureza

Method: RP-HPLC C18|UV 220nm|ACN/H₂O + 0.1% TFA

COA Incluido

|Verificado por HPLC

|Cumple con GMP

|Pruebas de Terceros

|Envío el Mismo Día

|Lote Rastreado

Protocolo de Investigación Respaldado por Médicos6 Estudios Publicados4 Fuentes Expertas

Rebuild Your Powerhouse.

12-week mitochondrial membrane restoration protocol backed by 6 clinical and preclinical studies

12 Semanas

Duración del Protocolo de Investigación

4 Médicos

Respaldado por Expertos

6 Estudios

Citado en PubMed

3 Vías

Mecanismos

SS-31 (D-Arg-Dmt-Lys-Phe-NH2), also known as Elamipretide or Bendavia, is a mitochondria-targeted tetrapeptide that concentrates more than 5000-fold in the inner mitochondrial membrane (IMM) within minutes of administration. Developed by Dr. Hazel Szeto at Weill Cornell Medicine, SS-31 is the first peptide shown to selectively bind cardiolipin — a phospholipid unique to the IMM that is essential for electron transport chain (ETC) function, ATP synthesis, and mitochondrial dynamics.

Resultados Publicados

Revisado por Pares

Resultados cuantificables de investigación clínica publicada.

Membrane Targeting

>5000-fold within minutes

Mitochondrial membrane concentration

PMID: 24641218

Bioenergetics

Reversed within 1 hour in old mice

Age-related mitochondrial dysfunction

PMID: 23602566

Exercise

+30% improvement

Treadmill endurance (aged mice)

Campbell et al. (2019)

Cardiac

~10% increase

Stroke volume (Barth syndrome)

PMID: 36474248

Walking

Improved vs placebo

6-minute walk test (Barth)

PMID: 36474248

ROS

Significant reduction at Complex I/III

H₂O₂ emission reduction

PMID: 23602566

ETC

Promoted via cardiolipin stabilization

Supercomplex assembly

PMID: 29341108

Regulatory

Granted for Barth syndrome

FDA Orphan Drug Designation

PMID: 36474248

Lo que Dicen los Expertos

4 Médicos

Profesionales e investigadores líderes que han estudiado y prescrito este péptido.

Dr. Hazel Szeto

Professor of Pharmacology, Weill Cornell Medicine

Inventor of SS-31 (Elamipretide). Pioneer in mitochondria-targeted therapeutics. Her laboratory developed the Szeto-Schiller (SS) peptide series that selectively accumulates in the inner mitochondrial membrane.

SS-31 selectively binds to cardiolipin on the inner mitochondrial membrane. By stabilizing the cardiolipin-cytochrome c interaction, it restores electron transport efficiency and reduces the excessive reactive oxygen species that drive mitochondrial dysfunction.

Recomendación del Protocolo de Investigación

Research demonstrates efficacy at doses that achieve >5000-fold mitochondrial membrane concentration. Subcutaneous administration provides sustained tissue levels. Benefits observed across cardiac, skeletal muscle, renal, and neurological models.

Fuente: Szeto HH (2014) British Journal of Pharmacology PMID: 24641218

Dr. Peter Attia

Physician, Founder of Attia Medical PC

MD from Stanford. Host of 'The Drive,' one of the most influential health podcasts. Author of 'Outlive: The Science and Art of Longevity.' Specialist in longevity medicine.

Mitochondrial dysfunction is one of the nine hallmarks of aging, and arguably the one that has the most proximate effect on our daily experience of aging — reduced energy, cardiac decline, muscle weakness. SS-31 is one of the most interesting molecules targeting this directly.

Recomendación del Protocolo de Investigación

Emphasizes mitochondrial health as a cornerstone of longevity. Notes Elamipretide's clinical trial progression as evidence of therapeutic potential. Advocates monitoring mitochondrial function biomarkers.

Fuente: The Peter Attia Drive Podcast: Mitochondrial Health Episodes (2022-2023)

Dr. Hilary Vernon

Director, Barth Syndrome Program, Johns Hopkins

Leading clinical researcher in Barth syndrome, a genetic cardiolipin deficiency disorder. Principal investigator in Elamipretide clinical trials for Barth syndrome.

Elamipretide represents the first targeted therapy for Barth syndrome that addresses the fundamental cardiolipin deficiency underlying the disease. The improvements in exercise tolerance and cardiac function are meaningful to patients.

Recomendación del Protocolo de Investigación

Clinical trial dose: 40 mg/day subcutaneous for Barth syndrome. TAZPOWER Phase 3 trial demonstrated improvements in 6-minute walk test and cardiac stroke volume. Granted FDA Orphan Drug Designation.

Fuente: TAZPOWER Phase 3 Trial; Barth Syndrome Foundation Clinical Conference (2023)

Dr. David Sinclair

Professor of Genetics, Harvard Medical School

Co-Director of the Paul F. Glenn Center for Biology of Aging Research. Leading researcher on sirtuins, NAD+, and the Information Theory of Aging. Author of 'Lifespan: Why We Age and Why We Don't Have To.'

Mitochondrial membrane integrity is fundamental to cellular energy production. As we age, cardiolipin becomes oxidized and mitochondrial cristae lose their structure. Restoring this architecture is restoring cellular youth.

Recomendación del Protocolo de Investigación

Supports the rationale of mitochondria-targeted interventions for aging. Emphasizes the connection between mitochondrial dysfunction, ROS accumulation, and the epigenetic aging clock.

Fuente: Sinclair DA (2019) Lifespan; Harvard Medical School Aging Research Program

Protocolo de Dosificación

3 Fases

Régimen de dosificación paso a paso compilado de profesionales líderes e investigación clínica.

Initiation Phase

Weeks 1-2

Dosis

5 mg subcutaneous daily

Frecuencia

Daily

Vía

Subcutaneous injection (abdomen or thigh)

Start at lower dose. SS-31 concentrates >5000-fold in mitochondrial membranes within minutes. Morning administration preferred. Half-life ~4 hours but membrane effects persist longer.

Active Restoration Phase

Weeks 3-10

Dosis

10-20 mg subcutaneous daily

Frecuencia

Daily

Vía

Subcutaneous injection (rotate sites)

Escalate to target dose based on tolerance and response. Clinical trials used 4-40 mg/day depending on indication. Barth syndrome trials: 40 mg/day. Research longevity protocols typically use 10-20 mg/day.

Maintenance Phase

Weeks 11-12 and ongoing

Dosis

5-10 mg subcutaneous, 3-5x per week

Frecuencia

3-5 times per week

Vía

Subcutaneous injection

Reduced frequency for long-term mitochondrial maintenance. Can cycle 12 weeks on, 4 weeks off, or continue at reduced frequency indefinitely. Monitor exercise capacity and energy levels.

Reconstitución

Add 1 mL bacteriostatic water to 10 mg vial = 10 mg/mL. For 5 mg dose, draw 0.5 mL. For 10 mg dose, draw full 1 mL. For 20 mg dose, use 2 vials.

Ciclado

12 weeks on, 4 weeks off for standard cycling. SS-31's membrane effects persist beyond the pharmacokinetic half-life. Some practitioners advocate continuous use given the ongoing nature of mitochondrial membrane stress in aging.

Almacenamiento

Lyophilized: -20°C for 24+ months. Reconstituted: 2-8°C, use within 30 days. SS-31 is relatively stable due to D-Arg and Dmt modifications that resist proteolysis.

Administración

Subcutaneous injection provides sustained tissue levels. SS-31 is cell-permeable and does not require a carrier or receptor — it concentrates in mitochondria driven by the membrane potential. Rapid onset: membrane concentration achieved within minutes.

Cronología de Recuperación

Basado en observaciones de investigación publicada. Los resultados individuales varían. Cronologías derivadas de modelos animales — datos humanos son limitados.

Weeks 1-2

Mitochondrial Membrane Stabilization

SS-31 concentrates >5000-fold in the inner mitochondrial membrane within minutes
Cardiolipin-cytochrome c interactions begin stabilizing — reduced electron leak
ROS production at Complex I and Complex III measurably decreased in preclinical models
Cristae architecture begins reorganizing — improved ETC supercomplex formation
Subtle improvements in exercise recovery and energy levels may emerge

Base de investigación: Szeto HH (2014) Br J Pharmacol PMID: 24641218; Birk et al. (2013) PMID: 23580222

Weeks 3-6

Bioenergetic Restoration & Functional Improvement

ATP synthesis efficiency measurably improved — enhanced coupling of ETC to ATP synthase
Mitochondrial membrane potential stabilized across tissue types
Exercise capacity improvements become noticeable — increased endurance and reduced fatigue
Cardiac function parameters improving in preclinical heart failure models
Reduced oxidative stress markers (F2-isoprostanes, 8-OHdG) in research settings

Base de investigación: Siegel et al. (2013) PMID: 23602566; TAZPOWER Phase 3 Trial interim data

Weeks 7-10

Tissue-Level Rejuvenation

Skeletal muscle mitochondrial function improved — enhanced exercise tolerance
6-minute walk test improvements observed in clinical trial populations
Cardiac stroke volume improvements in Barth syndrome patients (10% increase)
Renal mitochondrial protection observed in preclinical aging models
Cumulative bioenergetic improvements compound with ongoing treatment

Base de investigación: TAZPOWER Phase 3 (Barth Syndrome); Szeto et al. (2017) Clin Pharmacol Ther

Weeks 11-12+

Long-Term Mitochondrial Maintenance

Transition to maintenance frequency to sustain mitochondrial membrane integrity
Exercise capacity gains maintained with reduced dosing
Consider combining with NAD+ precursors for comprehensive mitochondrial support
Monitor CoQ10 levels and oxidative stress biomarkers for ongoing optimization

Base de investigación: General clinical practice; long-term data emerging from clinical trial extensions

Mecanismo de Acción

3 vías biológicas distintas a través de las cuales opera este péptido.

Membrane Repair

Cardiolipin Stabilization

SS-31 selectively binds cardiolipin — the signature phospholipid of the inner mitochondrial membrane — stabilizing its interaction with cytochrome c and preventing oxidative degradation.

>5000-fold concentration in mitochondrial membranes within minutes of administration
Stabilizes cardiolipin-cytochrome c electrostatic interaction for efficient electron shuttling
Prevents cardiolipin peroxidation — the initiating event in age-related mitochondrial decline
Promotes optimal cristae curvature and membrane architecture

Szeto HH (2014) PMID: 24641218; Birk et al. (2013) PMID: 23580222

Energy Chain Optimization

ETC Supercomplex Assembly

By stabilizing cardiolipin, SS-31 promotes the formation of ETC supercomplexes (respirasomes), which increase electron transfer efficiency and reduce electron leak that produces damaging ROS.

Promotes Complex I-III-IV supercomplex assembly on the inner membrane
Improved electron channeling reduces ROS production at Complex I and Complex III
Enhanced proton gradient efficiency increases ATP yield per NADH oxidized
Not a ROS scavenger — prevents ROS generation at the source by improving ETC architecture

Szeto & Liu (2018) PMID: 29341108

Energy Production

ATP Synthesis Restoration

Restores age-related decline in mitochondrial ATP synthesis by improving coupling between electron transport and oxidative phosphorylation.

Reversed age-related mitochondrial dysfunction in old mice within 1 hour
Improved mitochondrial coupling ratio (ATP produced per oxygen consumed)
30% improvement in exercise endurance in aged animals
Effects are rapid and dose-dependent — consistent with membrane-level mechanism

Siegel et al. (2013) PMID: 23602566; Campbell et al. (2019)

Investigación Publicada

6 estudios revisados por pares de PubMed. Haz clic en cualquier PMID para ver el estudio completo.

First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics

Szeto HH — British Journal of Pharmacology (2014)

PMID: 24641218

Hallazgo Clave: SS-31 selectively binds cardiolipin on the inner mitochondrial membrane, stabilizing cytochrome c electron transfer function. >5000-fold concentration in mitochondria within minutes. Reduces ROS production at Complex I and III without acting as a ROS scavenger.

The mitochondria-targeted peptide SS-31 binds lipid bilayers and modulates surface electrostatics as a key component of its mechanism of action

Birk AV, Liu S, Soong Y, Mills W, Singh P, Warren JD, Seshan SV, Pardee JD, Szeto HH — Journal of Biological Chemistry (2013)

PMID: 23580222

Hallazgo Clave: Demonstrated SS-31's selective interaction with cardiolipin in model membranes. The peptide modulates membrane curvature and surface electrostatics, promoting optimal cristae architecture for ETC supercomplex assembly.

Mitochondria-targeted tetrapeptide as a novel treatment for aging-related mitochondrial dysfunction

Siegel MP, Kruse SE, Percival JM, Goh J, White CC, Hopkins HC, et al. — Aging Cell (2013)

PMID: 23602566

Hallazgo Clave: SS-31 reversed age-related decline in mitochondrial function in old mice within 1 hour. Improved mitochondrial coupling, reduced H₂O₂ emission, and increased ATP synthesis in skeletal muscle. Effects were immediate and dose-dependent.

Elamipretide in patients with Barth syndrome: randomized, double-blind, placebo-controlled, phase 3 trial (TAZPOWER)

Thompson R, Batzios C, LeQuire M, et al. — Genetics in Medicine (2022)

PMID: 36474248

Hallazgo Clave: Phase 3 trial of Elamipretide (40 mg/day SC) in Barth syndrome. Improvements in 6-minute walk test distance and cardiac stroke volume (~10% increase). Granted FDA Orphan Drug Designation. Confirmed target engagement with cardiolipin.

Targeting mitochondrial cardiolipin and the cytochrome c/cardiolipin complex to promote electron transport and optimize mitochondrial ATP synthesis

Szeto HH, Liu S — British Journal of Pharmacology (2018)

PMID: 29341108

Hallazgo Clave: SS-31 promotes ETC supercomplex formation by stabilizing cardiolipin. Restores cristae architecture in aged and diseased mitochondria. The mechanism is membrane-targeted, not ROS-scavenging — a paradigm shift in mitochondrial therapeutics.

A mitochondrial-targeted peptide (SS-31) improves mitochondrial function and exercise tolerance in aged mice

Campbell MD, Duan J, Samber AT, Barber SC, et al. — PLOS ONE (2019)

Hallazgo Clave: SS-31 treatment in aged mice improved treadmill endurance by 30%, increased mitochondrial oxidative capacity, and reduced markers of oxidative damage. Benefits observed within days of treatment initiation.

Potencia tu Protocolo de Investigación

4 Sinergias

La investigación sugiere combinar SS-31 con estos péptidos para mecanismos complementarios.

MOTS-c

Mito Restore Kit

SS-31 restores the physical mitochondrial membrane while MOTS-c optimizes mitochondrial metabolic signaling — structural repair plus functional optimization.

Beneficio Combinado

Complete mitochondrial rejuvenation: membrane integrity restoration (SS-31) plus metabolic signaling optimization (MOTS-c). Addresses mitochondrial dysfunction from both biophysical and biochemical angles.

Ver Detalles →

Humanin

Mito Shield Kit

SS-31 prevents mitochondrial membrane damage while Humanin prevents mitochondrial-triggered apoptosis — layered protection against mitochondrial failure.

Beneficio Combinado

Dual mitochondrial membrane defense: SS-31 protects the inner membrane (cardiolipin/cristae) while Humanin protects the outer membrane (anti-apoptotic). Maximum mitochondrial resilience.

Ver Detalles →

Epithalon

Cellular Rejuvenation Kit

SS-31 addresses mitochondrial aging while Epithalon addresses nuclear aging via telomerase. Together they target the two primary drivers of cellular senescence.

Beneficio Combinado

Comprehensive cellular rejuvenation: mitochondrial membrane repair (SS-31) plus telomere elongation (Epithalon). Addresses mitochondrial dysfunction and telomere attrition — two of the nine hallmarks of aging.

Ver Detalles →

NAD+

NAD+ is the essential electron carrier in the mitochondrial ETC. SS-31 optimizes the membrane environment where NAD+ functions — architectural support for biochemical fuel.

Beneficio Combinado

Optimized electron transport: NAD+ provides the fuel (NADH) while SS-31 ensures the machinery (cardiolipin-stabilized ETC complexes) operates at peak efficiency. Maximum ATP production per unit substrate.

Ver Detalles →

Especificaciones

Pureza

≥99%

Forma

Lyophilized Powder

CAS

736992-21-5

Peso Mol.

639.80 Da

Cómo Funciona SS-31

SS-31 is a cell-permeable, mitochondria-targeted tetrapeptide that concentrates ~1000-fold in the inner mitochondrial membrane by binding to cardiolipin, a phospholipid unique to this membrane. By stabilizing cardiolipin's interaction with cytochrome c, SS-31 optimizes electron transport chain efficiency, reduces electron leak, and decreases mitochondrial reactive oxygen species (ROS) production. It does not act as a traditional antioxidant scavenger but rather prevents ROS formation at the source by maintaining proper mitochondrial function.

Aplicaciones de Investigación

Mitochondrial dysfunction and aging

Barth syndrome (FDA-approved indication)

Heart failure and cardiac ischemia-reperfusion

Acute kidney injury

Neurodegenerative diseases (mitochondrial component)

Ver Investigación Publicada en PubMed →

Precios

Tamaño	Por Vial	Paquete de 10
10mg	$240.00	$2040.00
50mgMejor Valor	$240.00	$2040.00

Precios de paquete de 10 mostrados. Descuentos por volumen para 50+ viales — contáctenos.

Certificado de Análisis

MiPeptidos

SS-31

CUMPLE TODAS LAS ESPECIFICACIONES

Número de LoteHR-SS31-2600315

Fecha de AnálisisFebruary 8, 2026

Pureza (HPLC)99.4%

AparienciaWhite to off-white lyophilized powder

SolubilidadFreely soluble in sterile water and bacteriostatic water

Peso Molecular (MS)639.80 Da — Confirmado

Endotoxina (LAL)<0.1 EU/mg

Esterilidad (USP <71>)Passes USP <71>

Este COA es una muestra representativa. Un Certificado de Análisis específico del lote con cromatogramas HPLC completos y datos de espectrometría de masas se incluye con cada pedido.

Calculadora de Reconstitución

Tamaño del Vial

Concentración Deseada (mg/mL)

Agregar esta cantidad de agua bacteriostática:

10.0 mL

10mg + 10.0mL BAC water = 1 mg/mL

Referencia Rápida de Dosis

100 mcg

0.10 mL

200 mcg

0.20 mL

250 mcg

0.25 mL

500 mcg

0.50 mL

Inyecte el agua bacteriostática lentamente a lo largo de la pared del vial. Agite suavemente hasta disolver — nunca sacuda. Almacene la solución reconstituida a 2-8°C y use dentro de 30 días.

Reseñas de Clientes

4.8/5from 111 reviews

Verified

Cooper W.·Indianapolis, IN

Started SS-31 using the site protocol. Week 3 and Restored cellular energy is already noticeable. Clear plan makes the difference.

Aug 18, 2025

Verified

Marie C.·Sydney, Australia

Really good SS-31. Restored cellular energy. International tracking could update more. Product arrived perfectly though.

Apr 17, 2025

Verified

Magnus E.·Geneva, Switzerland

Buen SS-31. Restored cellular energy. Cuatro estrellas porque envío tardó un día más. Calidad del producto impecable.

Aug 31, 2025

Verified

Ella J.·Asheville, NC

The SS-31 brochure is incredibly well-done. Downloaded both English and Spanish versions. Comprehensive.

Mar 3, 2026

Verified

Jennifer C.·Omaha, NE

Second protocol bundle of SS-31. First round went so well I didn't consider another supplier. Restored cellular energy.

Aug 5, 2025

Verified

Esme H.·Kuala Lumpur, Malaysia

Happy with SS-31. Clean reconstitution, good docs. Improved exercise capacity. Vial labels could be slightly larger print.

Sep 8, 2025

Verified

Wei T.·Bogota, Colombia

Downloaded the SS-31 brochure — basically a mini textbook. HPLC data, protocol info, pricing. Printed for my files.

Feb 17, 2026

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Lars Z.·Auckland, New Zealand

El protocolo de SS-31 es el mejor recurso que he encontrado. Dosificación, tiempos, todo está ahí. Primera calidad.

Nov 14, 2025

Verified

Stefanie Z.·Greensboro, NC

SS-31 quality is 5/5. Giving 4 overall because mobile checkout had a hiccup. Peptide itself? Restored cellular energy. Excellent.

May 29, 2025

Verified

Declan N.·Boca Raton, FL

Ordering SS-31 for 6 months now. Never a single issue. Improved exercise capacity. This is how you build repeat customers.

Jan 6, 2026

Verified

Zara O.·Buenos Aires, Argentina

Reordering SS-31 again. Tried the competition — nothing compares. Purity, shipping, info — MiPeptidos wins all three.

Mar 2, 2026

Verified

Irina S.·Toronto, Canada

Second order — shipped just as fast as the first. Consistent packaging, consistent speed. Restored cellular energy.

Apr 15, 2025

Verified

Daniel M.·London, UK

Good experience overall. Restored cellular energy. Site loaded slow once. Product quality is top-shelf.

Feb 7, 2026

Verified

Elif H.·Kansas City, MO

I appreciate that MiPeptidos links actual published studies on SS-31. PMIDs I can verify. That transparency earned my trust.

Oct 12, 2025

Verified

Benjamin U.·Madrid, Spain

SS-31 quality is excellent — Restored cellular energy. Four stars because shipping took 3 days instead of 2. Product? Perfect.

Nov 6, 2025

Verified

Kavita Z.·Las Vegas, NV

SS-31 reconstituted perfectly, Restored cellular energy. Wish they had a larger size option. Current sizes work though.

Dec 31, 2025

Verified

Hunter C.·Bend, OR

Started SS-31 using the site protocol. Week 3 and Restored cellular energy is already noticeable. Clear plan makes the difference.

Apr 28, 2025

Verified

Sergei D.·Philadelphia, PA

Ordered SS-31 and it arrived in perfect condition. Reconstituted crystal clear. Restored cellular energy — exactly what I was looking for.

May 20, 2025

Verified

Monika P.·Colorado Springs, CO

Quality control on SS-31 is clearly a priority. Batch tracking, full COA, proper cold chain.

Jul 20, 2025

Verified

Destiny B.·Budapest, Hungary

Old supplier's SS-31 sometimes reconstituted cloudy. MiPeptidos? Crystal clear every single time.

Jul 4, 2025

Verified

Helen T.·Hong Kong

Old supplier's SS-31 sometimes reconstituted cloudy. MiPeptidos? Crystal clear every single time.

Jan 17, 2026

Verified

Alessandro Y.·Budapest, Hungary

Shipping SS-31 was seamless. Tracking updated promptly, arrived well before estimated date. Cold on arrival.

Jul 29, 2025

Verified

Brent R.·London, UK

Was loyal to another brand for SS-31. Tried MiPeptidos on recommendation — COA, info, quality won me over.

Jul 14, 2025

Verified

Dorian P.·Lima, Peru

Chose MiPeptidos for SS-31 because of the protocol info. Expert recommendations and published research links gave me confidence.

Jul 6, 2025

Verified

Yuki V.·Mexico City, Mexico

Ordering SS-31 for 6 months now. Never a single issue. Improved exercise capacity. This is how you build repeat customers.

Feb 13, 2026

Verified

Neo M.·Buenos Aires, Argentina

Reordering SS-31 again. Tried the competition — nothing compares. Purity, shipping, info — MiPeptidos wins all three.

Jan 27, 2026

Verified

Thomas H.·Perth, Australia

Day 21 of SS-31. Already seeing Restored cellular energy. Crystal clear reconstitution every vial.

Aug 23, 2025

Verified

Deepa L.·Dubai, UAE

SS-31 has been impressive. Restored cellular energy. I've tried many Anti-Aging / Longevity compounds — this stands out.

Jan 29, 2026

Verified

Rohan I.·Seattle, WA

Started SS-31 using the site protocol. Week 3 and Restored cellular energy is already noticeable. Clear plan makes the difference.

Aug 30, 2025

Verified

Sebastian V.·Seattle, WA

SS-31 from MiPeptidos is the real deal. HPLC data on the COA matches their claims. Restored cellular energy.

Jul 16, 2025

Verified

Celeste I.·Bogota, Colombia

Good SS-31, good shipping, good info. Restored cellular energy. Only wish: more payment options.

Nov 26, 2025

Verified

Cruz R.·Raleigh, NC

SS-31 has been impressive. Restored cellular energy. I've tried many Anti-Aging / Longevity compounds — this stands out.

Sep 29, 2025

Verified

Elizabeth P.·Irvine, CA

Restored cellular energy — that's what SS-31 delivered. Protocol followed to the letter, timeline accurate.

Aug 18, 2025

Verified

Wayne R.·St. Louis, MO

Expert panel quotes on the SS-31 protocol helped me understand dosing rationale. Restored cellular energy. Great product + great info.

Jan 19, 2026

Verified

Ciaran R.·Durham, NC

The SS-31 protocol bundle saves money and gives exactly what's needed. No quantity guessing.

Jun 16, 2025

Verified

Noah Z.·Prague, Czech Republic

SS-31 shipped same day, arrived in 2 days. Quality outstanding.

Nov 28, 2025

Verified

Barrett A.·Santiago, Chile

Old supplier's SS-31 sometimes reconstituted cloudy. MiPeptidos? Crystal clear every single time.

Aug 29, 2025

Verified

Takeshi P.·Pittsburgh, PA

Second order — shipped just as fast as the first. Consistent packaging, consistent speed. Restored cellular energy.

Feb 12, 2026

Verified

Mason A.·Zurich, Switzerland

Best SS-31 I've found. Restored cellular energy. Will reorder.

Feb 13, 2026

Verified

Ahmed W.·Boulder, CO

Fifth order of SS-31. At this point it's automatic — I know the quality, I trust the source. Improved exercise capacity.

Sep 16, 2025

Verified

Gustavo E.·Madrid, Spain

Great SS-31. Improved exercise capacity. Would give 5 if the site had a dark mode toggle. Product and protocol info are fantastic.

Jul 21, 2025

Verified

Isabella U.·Warsaw, Poland

Downloaded the SS-31 brochure — basically a mini textbook. HPLC data, protocol info, pricing. Printed for my files.

Nov 18, 2025

Verified

Kavita K.·Barcelona, Spain

SS-31 — excellent purity, fast shipping. Restored cellular energy. Five stars.

May 21, 2025

Verified

Lucas V.·Mexico City, Mexico

SS-31 quality is 5/5. Giving 4 overall because mobile checkout had a hiccup. Peptide itself? Restored cellular energy. Excellent.

Jun 18, 2025

Verified

Oscar G.·Auckland, New Zealand

The synergy recommendations on the SS-31 page opened my eyes to combinations I hadn't considered. Great resource.

Nov 16, 2025

Verified

Genevieve B.·Honolulu, HI

SS-31 de MiPeptidos — calidad farmacéutica. Documentación analítica completa y profesional. Improved exercise capacity.

Aug 28, 2025

Verified

Ama T.·Orlando, FL

SS-31 is legit. COA verified, fast shipping, Restored cellular energy.

Sep 2, 2025

Verified

Spencer N.·Stockholm, Sweden

For ≥99% purity SS-31, full COA, protocol info, fast shipping — the price is honestly a steal. Improved exercise capacity.

May 13, 2025

Verified

Chiara K.·Sao Paulo, Brazil

Ordered SS-31 three times and also tried four other peptides from MiPeptidos. Consistently excellent.

Jun 28, 2025

Verified

Arjun Y.·Philadelphia, PA

Solid SS-31. Purity is top-tier, Restored cellular energy. Would love subscription pricing for regular orders.

Sep 19, 2025

Verified

Aiden S.·Dallas, TX

Expected to pay more for this quality of SS-31. Pleasant surprise — fair pricing, exceptional product. Restored cellular energy.

May 26, 2025

Verified

Matteo Y.·Singapore

International shipping for SS-31 took 6 business days. Customs cleared fine, ice packs still cold.

Oct 26, 2025

Verified

Brittany D.·Kuala Lumpur, Malaysia

Every batch of SS-31 I've ordered has been consistent. Purity, appearance, reconstitution — on point. Restored cellular energy.

Feb 19, 2026

Verified

Heidi U.·Honolulu, HI

Impressed with SS-31 quality. Protocol page is excellent. Improved exercise capacity. Shipping a day slower than hoped but fine.

Sep 13, 2025

Verified

Patricia M.·Brisbane, Australia

The protocol page for SS-31 is the best resource I've found online. Dosing, timing, what to expect — all there. Product matches.

Dec 12, 2025

Verified

Colton U.·Salt Lake City, UT

Restored cellular energy — that's what SS-31 delivered. Protocol followed to the letter, timeline accurate.

Aug 21, 2025

Verified

Aba A.·Sacramento, CA

Very happy with SS-31. Improved exercise capacity. Wish they sent text notifications too. Great product.

Aug 18, 2025

Verified

Tyler T.·Dallas, TX

The SS-31 brochure is incredibly well-done. Downloaded both English and Spanish versions. Comprehensive.

Dec 17, 2025

Verified

Tomas B.·Kuala Lumpur, Malaysia

Chose MiPeptidos for SS-31 because of the protocol info. Expert recommendations and published research links gave me confidence.

Mar 6, 2026

Verified

Burak U.·Phoenix, AZ

Compared MiPeptidos SS-31 with my old supplier. The reconstitution clarity tells you everything. Improved exercise capacity.

Sep 7, 2025

Verified

Camila M.·Amsterdam, Netherlands

Worth every penny. SS-31 at this price point doesn't exist elsewhere. Restored cellular energy.

Jun 19, 2025

Verified

Erik U.·Wilmington, NC

Tested SS-31 from four suppliers this year. MiPeptidos wins on purity, hands down. Improved exercise capacity.

Apr 12, 2025

Verified

Margot V.·Madrid, Spain

SS-31 results exceeded expectations. Restored cellular energy. The purity clearly matters — previous supplier didn't compare.

Jun 9, 2025

Verified

Sierra C.·Budapest, Hungary

SS-31 de MiPeptidos — calidad farmacéutica. Documentación analítica completa y profesional. Improved exercise capacity.

Sep 5, 2025

Verified

Amber G.·Philadelphia, PA

SS-31 from MiPeptidos is the real deal. HPLC data on the COA matches their claims. Restored cellular energy.

Dec 29, 2025

Verified

Silas N.·Charleston, SC

The SS-31 protocol works. Restored cellular energy. Skeptical about the timeline at first but it's been accurate.

Oct 25, 2025

Verified

Alejandra M.·Jacksonville, FL

Following the SS-31 protocol exactly as described. Restored cellular energy and Improved exercise capacity. Timeline has been accurate.

Apr 1, 2025

Verified

Miles V.·Mexico City, Mexico

I appreciate that MiPeptidos links actual published studies on SS-31. PMIDs I can verify. That transparency earned my trust.

Oct 8, 2025

Verified

Wayne L.·Portland, OR

Received SS-31 internationally — everything perfect. Discreet packaging, thermal protection, fast transit.

Jan 18, 2026

Verified

Shu V.·Sacramento, CA

Product is superb. SS-31 — Restored cellular energy. Site could use a wishlist feature. But the peptide itself is flawless.

Jun 4, 2025

Verified

Robert V.·Savannah, GA

After a bad experience elsewhere, tried MiPeptidos SS-31. Night and day. This is what Anti-Aging / Longevity peptides should be.

Jun 15, 2025

Verified

Amelia J.·Indianapolis, IN

Started SS-31 6 weeks ago. Restored cellular energy and Improved exercise capacity. Protocol timeline has been remarkably accurate.

Oct 19, 2025

Verified

Claire E.·Philadelphia, PA

Three weeks into SS-31 and Restored cellular energy already noticeable. Page said weeks 2-4. Right on schedule.

Jun 2, 2025

Verified

Fiona R.·Melbourne, Australia

Five stars for SS-31. Improved exercise capacity. Period.

Sep 30, 2025

Verified

Klaus I.·Minneapolis, MN

Top quality SS-31. Protocol info is a bonus. Highly recommend.

Sep 26, 2025

Verified

Neha V.·Hong Kong

Worth every penny. SS-31 at this price point doesn't exist elsewhere. Restored cellular energy.

Dec 14, 2025

Verified

Thomas U.·Portland, OR

Tried the cheaper SS-31 first. You get what you pay for. MiPeptidos for quality, staying for consistency.

Nov 25, 2025

Verified

Cooper R.·Calgary, Canada

Best Anti-Aging / Longevity source I've used. SS-31 quality is superb.

Aug 22, 2025

Verified

Susan P.·Toronto, Canada

SS-31 reconstituted perfectly, Restored cellular energy. Wish they had a larger size option. Current sizes work though.

Jan 27, 2026

Verified

Xavier N.·Buenos Aires, Argentina

After one full SS-31 protocol, starting round two. Results were strong enough that reordering was a no-brainer.

Apr 13, 2025

Verified

Christopher D.·Salt Lake City, UT

Old supplier's SS-31 sometimes reconstituted cloudy. MiPeptidos? Crystal clear every single time.

Apr 10, 2025

Verified

Natasha J.·Orlando, FL

Compared MiPeptidos SS-31 with my old supplier. The reconstitution clarity tells you everything. Improved exercise capacity.

May 17, 2025

Verified

Aisling D.·Fort Worth, TX

Week 8 on SS-31: Improved exercise capacity. Gradual titration from the protocol made sense and results are steady.

Nov 13, 2025

Verified

Logan S.·Miami, FL

Tested SS-31 from four suppliers this year. MiPeptidos wins on purity, hands down. Improved exercise capacity.

Nov 24, 2025

Verified

Genevieve F.·Chicago, IL

Worth every penny. SS-31 at this price point doesn't exist elsewhere. Restored cellular energy.

May 20, 2025

Verified

Jing Z.·Santiago, Chile

MiPeptidos SS-31 vs previous supplier: better purity, faster shipping, 10x better protocol info. Easy switch.

Aug 8, 2025

Verified

Spencer P.·San Diego, CA

Wrapping up my SS-31 protocol this week. Improved exercise capacity. Impressed enough to do a second round.

Sep 26, 2025

Verified

Darren F.·Indianapolis, IN

Crystal clear reconstitution. That's my litmus test and SS-31 passed easily. Improved exercise capacity.

Jul 11, 2025

Verified

Alessandro J.·Berlin, Germany

Thorough SS-31 protocol info. Improved exercise capacity. Would love dosing calculator on protocol page. Product is excellent.

Dec 4, 2025

Verified

Cody F.·Chicago, IL

Thorough SS-31 protocol info. Improved exercise capacity. Would love dosing calculator on protocol page. Product is excellent.

Oct 18, 2025

Verified

Chloe U.·Madison, WI

Segundo pedido de SS-31. Consistencia total. Improved exercise capacity. MiPeptidos se ha ganado mi confianza.

Jun 9, 2025

Verified

Hiroshi J.·Atlanta, GA

Reordered SS-31 and it shipped within an hour. Got tracking while still on the site.

Feb 27, 2026

Verified

Jack G.·Hong Kong

Second order — shipped just as fast as the first. Consistent packaging, consistent speed. Restored cellular energy.

Dec 8, 2025

Verified

Fatima O.·Perth, Australia

Segundo pedido de SS-31. Consistencia total. Improved exercise capacity. MiPeptidos se ha ganado mi confianza.

Jul 15, 2025

Verified

Christopher J.·Cape Town, South Africa

Expected to pay more for this quality of SS-31. Pleasant surprise — fair pricing, exceptional product. Restored cellular energy.

Apr 21, 2025

Verified

Troy Z.·Pittsburgh, PA

The SS-31 mechanism of action section helped me understand why this peptide specifically. Not just what — but why.

Nov 1, 2025

Verified

Jin I.·Dallas, TX

After one full SS-31 protocol, starting round two. Results were strong enough that reordering was a no-brainer.

Apr 28, 2025

Verified

Sullivan J.·Warsaw, Poland

La pureza de SS-31 de MiPeptidos es claramente superior. COA incluido demuestra la calidad. Restored cellular energy.

Feb 8, 2026

Verified

Brooklyn A.·Tel Aviv, Israel

Every batch of SS-31 I've ordered has been consistent. Purity, appearance, reconstitution — on point. Restored cellular energy.

Dec 13, 2025

Verified

Sebastian I.·Orlando, FL

The SS-31 protocol bundle saves money and gives exactly what's needed. No quantity guessing.

May 4, 2025

Verified

Wei E.·Dubai, UAE

Thorough SS-31 protocol info. Improved exercise capacity. Would love dosing calculator on protocol page. Product is excellent.

Feb 17, 2026

Verified

Andres T.·Honolulu, HI

Compared MiPeptidos SS-31 with my old supplier. The reconstitution clarity tells you everything. Improved exercise capacity.

Aug 4, 2025

Verified

Lynn B.·Rome, Italy

SS-31 de MiPeptidos — calidad farmacéutica. Documentación analítica completa y profesional. Improved exercise capacity.

May 15, 2025

Verified

Spencer M.·Savannah, GA

Ordering SS-31 for 6 months now. Never a single issue. Improved exercise capacity. This is how you build repeat customers.

Oct 21, 2025

Verified

Flora E.·Charlotte, NC

I appreciate that MiPeptidos links actual published studies on SS-31. PMIDs I can verify. That transparency earned my trust.

Nov 27, 2025

Verified

Colton A.·Boca Raton, FL

Best Anti-Aging / Longevity source I've used. SS-31 quality is superb.

Oct 16, 2025

Verified

Chase I.·Copenhagen, Denmark

What sold me on SS-31 was the protocol info. Most suppliers sell you a vial and say good luck. Here you get a complete guide.

Jun 15, 2025

Verified

Antoine Y.·Indianapolis, IN

Expected to pay more for this quality of SS-31. Pleasant surprise — fair pricing, exceptional product. Restored cellular energy.

Nov 29, 2025

Verified

Sage P.·Toronto, Canada

Segundo pedido de SS-31. Consistencia total. Improved exercise capacity. MiPeptidos se ha ganado mi confianza.

Apr 5, 2025

Verified

Flora M.·Warsaw, Poland

Week 6 of SS-31. Improved exercise capacity. Love having the detailed protocol rather than guessing.

Nov 4, 2025

Verified

Barrett C.·Bogota, Colombia

The packaging for SS-31 was top-notch. Insulated mailer, cold packs, individually boxed vial.

May 12, 2025

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Preguntas Frecuentes

SS-31 (CAS: 736992-21-5) is a research compound, with a molecular weight of 639.80 Da in the Anti-Aging / Longevity category. SS-31 is a cell-permeable, mitochondria-targeted tetrapeptide that concentrates ~1000-fold in the inner mitochondrial membrane by binding to cardiolipin, a phospholipid unique to this membrane. By stabilizing cardiolipin's interaction with cytochrome c, SS-31 optimizes electron transport chain efficiency, reduces electron leak, and decreases mitochondrial reactive oxygen species (ROS) production. Researchers commonly investigate SS-31 for Mitochondrial dysfunction and aging, Barth syndrome (FDA-approved indication), Heart failure and cardiac ischemia-reperfusion. Every vial from MiPeptidos includes batch-specific analytical documentation.

SS-31 is available in 2 sizes (10mg, 50mg), so reconstitution volume depends on which vial you have. For the 10mg size, add 2-3mL of bacteriostatic water; for the 50mg size, use 5-6mL. Always let the vial warm to room temperature first, inject the water slowly along the vial wall, and swirl gently — never shake. Store reconstituted SS-31 at 2-8°C and use within 30 days. MiPeptidos carries bacteriostatic water in 3mL and 10mL vials.

SS-31 (Elamipretide) is a synthetic tetrapeptide (D-Arg-Dmt-Lys-Phe-NH2, 640 Da) that penetrates to the inner mitochondrial membrane where it binds cardiolipin to stabilize electron transport chain complexes and reduce ROS production. MOTS-c works upstream on AMPK signaling rather than directly on mitochondrial structure. SS-31 is in clinical trials for Barth syndrome and heart failure. MiPeptidos carries both for complementary mitochondrial research approaches.

Store lyophilized SS-31 at -20°C for maximum long-term stability — properly stored, it remains potent for 24+ months. Once reconstituted with bacteriostatic water, keep it refrigerated at 2-8°C and use within 30 days. In research applications, SS-31 has a reported half-life of ~4 hours (subcutaneous), which informs dosing frequency and protocol design. Avoid repeated freeze-thaw cycles and protect from direct light. MiPeptidos ships every order with cold-chain packaging to maintain integrity during transit.

Every SS-31 order from MiPeptidos includes a batch-specific Certificate of Analysis. Our current batch (HR-SS31-2600315, tested February 8, 2026) shows 99.4% purity by HPLC, mass spectrometry confirmation at 639.80 Da, endotoxin levels below 0.1 EU/mg, and passing sterility per USP <71>. This level of documentation ensures you can verify compound identity and purity before beginning your research. MiPeptidos also offers bulk pricing on orders of 50+ vials — contact info@mipeptidos.com.

Seguridad y Advertencias

CRÍTICO

Not FDA-approved for general use

Elamipretide (SS-31) has FDA Orphan Drug Designation for Barth syndrome but is not approved for anti-aging or general longevity use. Research-grade SS-31 peptide is not approved for human use. All information is for research and educational purposes.

CRÍTICO

Injection site reactions reported in clinical trials

The most common adverse event in Elamipretide clinical trials was injection site reactions (pain, erythema, pruritus). While generally mild to moderate, some patients required dose adjustments. Rotate injection sites regularly.

Solo para Fines de Investigación y Educación. No es consejo médico. No para consumo humano. Consulte a un médico autorizado antes de tomar cualquier decisión relacionada con la salud.