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Análisis de Pureza HPLC
Oxytocin Acetate
CAS: 50-56-6
Estudiado para vínculos neuroendocrinos y señalización social
Oxytocin Acetate is a research peptide in the sexual health / hormonal category. Oxytocin is a nonapeptide hormone produced in the hypothalamic paraventricular and supraoptic nuclei. MiPeptidos offers Oxytocin Acetate in 3 sizes with 99.8% verified purity and full analytical documentation.
- Stronger emotional closeness
- Reduced social anxiety
- Enhanced trust and empathy
- Improved intimacy quality
Studies report feeling calmer and more socially open within 30-45 minutes of use, with effects lasting 2-4 hours. Over weeks 1-4, research suggests improved emotional responses during social interactions and reduced stress reactivity. By weeks 6-8, studies report a noticeable shift in relationship quality and social confidence.
$24.95/vial · Everything you need to start
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Análisis de Pureza HPLC
Deepen Every Connection.
8-week neuroendocrine protocol backed by 5 clinical studies in social cognition and bonding
Oxytocin is a naturally occurring nonapeptide hormone produced in the paraventricular and supraoptic nuclei of the hypothalamus and released from the posterior pituitary. Often called the 'bonding hormone,' oxytocin plays fundamental roles in social attachment, trust, empathy, sexual arousal, orgasm, uterine contraction, and lactation.
Resultados Publicados
Revisado por ParesResultados cuantificables de investigación clínica publicada.
Lo que Dicen los Expertos
4 MédicosProfesionales e investigadores líderes que han estudiado y prescrito este péptido.
Dr. Paul Zak
Professor of Economics, Psychology, and Management, Claremont Graduate University
Known as 'Dr. Love.' Author of 'The Moral Molecule.' Pioneer in neuroeconomics research linking oxytocin to trust, generosity, and social bonding. TED speaker with 2M+ views.
Oxytocin is the neurochemical signature of trust. When oxytocin rises, people become more generous, more empathetic, and more cooperative. It literally makes us more human in our interactions.
Oxytocin at 10-20 IU subcutaneous increases trust and generosity. Social context matters — oxytocin enhances in-group bonding but may increase wariness of out-groups.
Fuente: Zak et al. (2004) Neuroendocrinology Letters PMID: 15580166; 'The Moral Molecule' (2012)
Dr. Markus Heinrichs
Professor of Biological and Clinical Psychology, University of Freiburg
World leader in intranasal oxytocin research. Led the seminal 2005 Nature study demonstrating oxytocin increases trust. Over 200 publications on oxytocin and social behavior.
Oxytocin administration significantly increases trust among humans, thereby greatly increasing the benefits from social interactions. It also significantly reduces cortisol responses to social stress.
Standard subcutaneous dose: 10-20 IU. Administer 30-45 minutes before social interaction or assessment. Effects last 2-4 hours. Avoid daily use for extended periods — intermittent use preferred.
Fuente: Kosfeld et al. (2005) Nature PMID: 15931222; Heinrichs et al. (2003) Biological Psychiatry
Dr. C. Sue Carter
Distinguished University Scientist, Indiana University
Pioneer of oxytocin research in prairie voles. Discovered the role of oxytocin in pair bonding. Over 400 publications. Fundamentally shaped our understanding of the neurobiology of love.
Oxytocin is not a simple 'love hormone' — it's a complex neuromodulator that calibrates social engagement based on context. In safe contexts it promotes approach; in threatening contexts it can promote protective vigilance.
Context is critical for oxytocin's effects. It amplifies the salience of social cues — positive in positive environments, potentially anxiogenic in threatening ones. Research should always control for social context.
Fuente: Carter (1998) Neuroscience & Biobehavioral Reviews; Carter (2014) Psychoneuroendocrinology
Dr. Andrew Huberman
Professor of Neurobiology, Stanford University
Ph.D. in Neuroscience. Host of Huberman Lab, one of the most popular science podcasts globally.
Oxytocin increases pair bonding and synchrony between partners. It's released during physical touch, eye contact, and especially during orgasm. Exogenous oxytocin can partially mimic these effects, but the natural release during genuine social connection is more robust.
Subcutaneous oxytocin 10-20 IU enhances social bonding, reduces social anxiety, and improves empathy. Best used intermittently in the context of genuine social interaction — not as a daily supplement.
Fuente: Huberman Lab Podcast: The Science of Love, Desire, and Attachment (2022)
Protocolo de Dosificación
2 FasesRégimen de dosificación paso a paso compilado de profesionales líderes e investigación clínica.
Standard research dose is 10-20 IU subcutaneous. Administer 30-45 min before target social situation. Effects last 2-4 hours. Do not use daily.
Intermittent use preferred to prevent receptor desensitization. Use in context of meaningful social interactions for best results. Discontinue for 2-4 weeks periodically.
Add 2 mL bacteriostatic water to 5 mg vial. Calculate IU based on molecular weight (1 IU ≈ ~1.67 mcg). 10 IU ≈ 16.7 mcg. Use insulin syringe for precise measurement.
Intermittent use recommended: 2-4 doses per week for 4-6 weeks, then 2-4 weeks off. Chronic daily oxytocin use may downregulate OXTR expression. Episodic use mimics natural pulsatile release patterns.
Lyophilized: -20°C for 24+ months. Reconstituted: 2-8°C, use within 21-28 days. Oxytocin is relatively fragile — avoid repeated freeze-thaw. Protect from light and heat.
Subcutaneous injection (abdominal). Provides systemic oxytocin effects including peripheral tissue repair, anti-inflammatory action, and neuroendocrine modulation. Rotate injection sites.
Cronología de Recuperación
Basado en observaciones de investigación publicada. Los resultados individuales varían. Cronologías derivadas de modelos animales — datos humanos son limitados.
Acute Neuroendocrine Response
- Subcutaneous OT reaches systemic circulation within minutes, with effects observed within 30-45 minutes
- Reduced amygdala reactivity to threatening social stimuli within 45 minutes
- Increased eye gaze toward social stimuli, especially the eye region of faces
- Reduced cortisol response to social stress (Trier Social Stress Test)
- Enhanced feeling of calm and social receptivity lasting 2-4 hours
Base de investigación: Heinrichs et al. (2003) Biological Psychiatry; Kosfeld et al. (2005) Nature PMID: 15931222
Social Cognition Enhancement
- Improved recognition of positive social cues and facial expressions
- Enhanced empathic accuracy — better reading of others' emotional states
- Increased generosity and trust in interpersonal interactions
- Reduced social anxiety in structured social encounters
- Some studies report enhanced emotional intimacy with partners
Base de investigación: Domes et al. (2007) Biological Psychiatry PMID: 16904652; Guastella et al. (2008) Biological Psychiatry
Sustained Social & Sexual Enhancement
- Consistent pattern of improved social engagement when dosed before interactions
- Enhanced orgasm intensity reported in both sexes (OT surges naturally during orgasm)
- Reduced baseline anxiety in social contexts even between doses
- Pair bonding behaviors strengthened with consistent use in relationship context
- Some evidence of improved pain tolerance via oxytocinergic descending pain modulation
Base de investigación: Scheele et al. (2012) Journal of Neuroscience PMID: 23136407; Ohlsson et al. (2005) European Journal of Pain
Assessment & Intermittent Maintenance
- Evaluate subjective social well-being and relationship quality improvements
- Consider tapering to 1-2 doses per week for maintenance
- Natural OT system may be upregulated by positive social behaviors established during protocol
- Discontinuation does not produce withdrawal — returns to baseline social functioning
Base de investigación: General neuroendocrinology; OT receptor regulation literature
Mecanismo de Acción
3 vías biológicas distintas a través de las cuales opera este péptido.
OXTR Signaling in Limbic & Hypothalamic Circuits
Oxytocin binds OXTR (Gq-coupled) in the amygdala, nucleus accumbens, VTA, and PVN, modulating social salience, reward, and stress reactivity.
- Reduces amygdala reactivity to threatening social stimuli — lowers social fear
- Enhances dopaminergic reward signaling in nucleus accumbens during social interactions
- Activates VTA → NAc pathway that makes social engagement intrinsically rewarding
Kosfeld et al. (2005) PMID: 15931222; Labuschagne et al. (2010) PMID: 20393460
HPA Axis Stress Buffering
Oxytocin inhibits CRH release from the PVN and dampens HPA axis reactivity, providing a 'social buffering' effect that reduces cortisol responses to social stress.
- Directly inhibits CRH neuron activity in the PVN → reduced ACTH → reduced cortisol
- Trier Social Stress Test studies show 30-50% cortisol reduction with exogenous OT
- This stress-buffering effect is context-dependent — enhanced in supportive social environments
Heinrichs et al. (2003) Biological Psychiatry; Ditzen et al. (2009) Psychoneuroendocrinology
Sexual Arousal & Orgasm Enhancement
Oxytocin surges during sexual arousal and peaks dramatically at orgasm. Exogenous OT enhances genital blood flow, orgasm intensity, and post-coital bonding.
- Plasma OT levels increase 3-5x during orgasm in both sexes
- OT stimulates smooth muscle contraction in reproductive organs during orgasm
- Exogenous OT enhanced orgasm intensity and sexual satisfaction in RCT
Behnia et al. (2014) PMID: 24781441; Carmichael et al. (1987) J Clin Endocrinol Metab
Investigación Publicada
5 estudios revisados por pares de PubMed. Haz clic en cualquier PMID para ver el estudio completo.
Oxytocin increases trust in humans
Kosfeld M, Heinrichs M, Zak PJ, Fischbacher U, Fehr E — Nature (2005)
Hallazgo Clave: Landmark study: intranasal oxytocin (24 IU) significantly increased trust in a monetary trust game. OT subjects transferred 17% more money than placebo, indicating enhanced interpersonal trust.
Oxytocin improves 'mind-reading' in humans
Domes G, Heinrichs M, Michel A, Berger C, Herpertz SC — Biological Psychiatry (2007)
Hallazgo Clave: Intranasal oxytocin significantly improved the ability to infer the mental state of others from their eyes (Reading the Mind in the Eyes Test) — direct evidence of enhanced empathic accuracy.
Oxytocin modulates social distance between males and females
Scheele D, Striepens N, Gunturkun O, et al. — Journal of Neuroscience (2012)
Hallazgo Clave: Oxytocin promoted pair bonding fidelity: men in monogamous relationships maintained greater interpersonal distance from attractive women after OT vs placebo. Single men showed no effect.
Oxytocin attenuates amygdala reactivity to fear in generalized social anxiety disorder
Labuschagne I, Phan KL, Wood A, et al. — Neuropsychopharmacology (2010)
Hallazgo Clave: In patients with generalized social anxiety disorder, intranasal OT (24 IU) normalized amygdala hyperreactivity to fearful faces to levels comparable to healthy controls.
Effects of intranasal oxytocin on sexual function in men: a randomized controlled trial
Behnia B, Heinrichs M, Bergmann W, et al. — Journal of Clinical Psychopharmacology (2014)
Hallazgo Clave: Intranasal oxytocin (24 IU) significantly enhanced orgasm intensity, contentment after intercourse, and partner interaction quality in healthy men in a double-blind crossover trial.
Potencia tu Protocolo de Investigación
4 SinergiasLa investigación sugiere combinar Oxytocin Acetate con estos péptidos para mecanismos complementarios.
PT-141 activates central sexual arousal while oxytocin enhances emotional bonding, trust, and orgasm quality for comprehensive sexual wellness.
Addresses both physical arousal (PT-141) and emotional connection/orgasm intensity (oxytocin) — the two pillars of sexual satisfaction.
Kisspeptin optimizes reproductive hormones through HPG axis activation while oxytocin enhances the social/emotional dimensions of sexual function.
Hormonal optimization plus neuropsychological enhancement — addressing sexual function from both endocrine and central nervous system perspectives.
Selank reduces anxiety through GABA modulation while oxytocin enhances social approach behavior — together addressing social anxiety from two pathways.
Comprehensive social anxiety reduction: oxytocin makes social engagement more rewarding while selank reduces the underlying anxiety that inhibits social approach.
BPC-157 modulates dopamine and serotonin systems that interact with oxytocinergic signaling, and supports gut-brain axis health underlying neuroendocrine function.
Supports the neuroendocrine infrastructure underlying social bonding — BPC-157's neurotransmitter regulation may enhance oxytocin's prosocial effects.
Especificaciones
Cómo Funciona Oxytocin Acetate
Oxytocin is a nonapeptide hormone produced in the hypothalamic paraventricular and supraoptic nuclei. It acts through the oxytocin receptor (OXTR), a G protein-coupled receptor, to stimulate uterine smooth muscle contraction during labor, milk ejection during breastfeeding, and social bonding behaviors. In the CNS, oxytocin modulates social cognition, trust, empathy, pair bonding, and anxiety reduction through actions in the amygdala, nucleus accumbens, and prefrontal cortex. It also has anti-inflammatory and wound-healing properties.
Aplicaciones de Investigación
Precios
| Tamaño | Por Vial | Paquete de 10 | Ahorro |
|---|---|---|---|
2mgOferta | $21.95$30.00 | $186.57 | 27% descuento |
5mgOferta | $31.95$40.00 | $271.57 | 20% descuento |
10mgMejor ValorOferta | $44.95$50.00 | $382.07 | 10% descuento |
Precios de paquete de 10 mostrados. Descuentos por volumen para 50+ viales — contáctenos.
Certificado de Análisis
Este COA es una muestra representativa. Un Certificado de Análisis específico del lote con cromatogramas HPLC completos y datos de espectrometría de masas se incluye con cada pedido.
Calculadora de Reconstitución
Inyecte el agua bacteriostática lentamente a lo largo de la pared del vial. Agite suavemente hasta disolver — nunca sacuda. Almacene la solución reconstituida a 2-8°C y use dentro de 30 días.
Reseñas de Clientes
Preguntas Frecuentes
Seguridad y Advertencias
Contraindicated during pregnancy (research form)
Oxytocin causes uterine contractions. Only FDA-approved Pitocin under medical supervision should be used in obstetric settings. Research-grade oxytocin must not be used during pregnancy.
Blood pressure and cardiovascular effects
High doses of oxytocin can cause transient hypotension and reflex tachycardia. Use with caution in individuals with cardiovascular conditions. Monitor blood pressure with initial doses.
Solo para Fines de Investigación y Educación. No es consejo médico. No para consumo humano. Consulte a un médico autorizado antes de tomar cualquier decisión relacionada con la salud.
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