PT141 - Front - MiPeptidos
Sexual Health / Hormonal

PT141

CAS: 189691-06-3

PT141 is a research peptide in the sexual health / hormonal category. PT-141 is a cyclic heptapeptide melanocortin receptor agonist that activates MC3R and MC4R receptors in the central nervous system. MiPeptidos offers PT141 in 1 sizes with 99.3% verified purity and full analytical documentation.

Starting at
$28.95/vial
In Stock
Ships same day
Request Quote
≥99% Purity
COA Included
Third-Party Tested
Same-Day Shipping
CoA Included
HPLC Verified
GMP Compliant
Third-Party Tested
Same-Day Shipping
Batch Tracked

How PT141 Works

PT-141 is a cyclic heptapeptide melanocortin receptor agonist that activates MC3R and MC4R receptors in the central nervous system. Unlike PDE5 inhibitors which act on vascular smooth muscle, PT-141 acts directly on the hypothalamic melanocortin system to stimulate sexual desire and arousal through neural pathways. MC4R activation in the medial preoptic area and paraventricular nucleus triggers downstream signaling that enhances sexual motivation and arousal in both sexes.

Research Applications

1
Hypoactive sexual desire disorder (FDA-approved in women)
2
Central nervous system sexual arousal pathways
3
Melanocortin receptor pharmacology
4
Male erectile dysfunction via central mechanism
5
Comparison with peripheral vasodilator mechanisms
View Published Research on PubMed →

Pricing

SizePer Vial10-Pack
10mg
$28.95$210.95

Prices shown per vial from 10-pack. Volume discounts available for 50+ vials — contact us.

HPLC Purity Analysis

High-Performance Liquid Chromatography
99.3%purity
mAURetention Time (min)0250500750100005101520253099.3%
Method: RP-HPLC C18 ColumnDetection: UV 220nmMobile Phase: Acetonitrile/Water + 0.1% TFA

Certificate of Analysis

MiPeptidos
PT141
PASSES ALL SPECIFICATIONS
Batch NumberHR-PT14-2600315
Date of AnalysisMarch 27, 2026
Purity (HPLC)99.3%
AppearanceWhite to off-white lyophilized powder
SolubilityFreely soluble in sterile water and bacteriostatic water
Molecular Weight (MS)1025.16 Da — Confirmed
Endotoxin (LAL)<0.1 EU/mg
Sterility (USP <71>)Passes USP <71>

This COA is a representative sample. A batch-specific Certificate of Analysis with full HPLC chromatograms and mass spectrometry data is included with every MiPeptidos order.

Reconstitution Calculator

Add this much bacteriostatic water:
10.0 mL
10 mg PT141 + 10.0 mL BAC water = 1 mg/mL

Inject bacteriostatic water slowly along the vial wall. Gently swirl until dissolved — never shake. Store reconstituted solution at 2-8°C and use within 30 days.

Download Product Brochure

Get our detailed PT141 product brochure with specifications, research applications, HPLC analysis data, and reconstitution guide. Available in English and Spanish.

Customer Reviews

5.0/5from 1 review
Verified
Nicole Brennan·Las Vegas, NV

PT-141 (bremelanotide) from MiPeptidos is our melanocortin MC3R/MC4R agonist for sexual function research. The cyclic heptapeptide shows expected receptor activation profiles in our binding assays. Purity is 99.0% and th...

Feb 4, 2026
View All Reviews →

Frequently Asked Questions

PT141 (CAS: 189691-06-3) is a research compound, with a molecular weight of 1025.16 Da in the Sexual Health / Hormonal category. PT-141 is a cyclic heptapeptide melanocortin receptor agonist that activates MC3R and MC4R receptors in the central nervous system. Unlike PDE5 inhibitors which act on vascular smooth muscle, PT-141 acts directly on the hypothalamic melanocortin system to stimulate sexual desire and arousal through neural pathways. Researchers commonly investigate PT141 for Hypoactive sexual desire disorder (FDA-approved in women), Central nervous system sexual arousal pathways, Melanocortin receptor pharmacology. Every vial from MiPeptidos includes batch-specific analytical documentation.
To reconstitute your PT141 10mg vial, let it reach room temperature for about 15-20 minutes out of the freezer. Slowly inject 2-3mL of bacteriostatic water along the inside wall of the vial — never aim directly at the peptide cake. Gently swirl until the powder fully dissolves; never shake, as this can denature the peptide. Store reconstituted PT141 at 2-8°C and use within 30 days. MiPeptidos includes bacteriostatic water for purchase alongside all peptides.
PT-141 (Bremelanotide) is a cyclic heptapeptide metabolite of Melanotan II specifically optimized for MC4R (melanocortin-4 receptor) activation in the CNS, producing sexual arousal effects without the melanogenesis (tanning) caused by MC1R activation. Melanotan II activates both MC1R (tanning) and MC4R (sexual function). PT-141 is FDA-approved as Vyleesi for hypoactive sexual desire disorder. MiPeptidos carries both for melanocortin pathway research.
Store lyophilized PT141 at -20°C for maximum long-term stability — properly stored, it remains potent for 24+ months. Once reconstituted with bacteriostatic water, keep it refrigerated at 2-8°C and use within 30 days. In research applications, PT141 has a reported half-life of ~2.7 hours, which informs dosing frequency and protocol design. Avoid repeated freeze-thaw cycles and protect from direct light. MiPeptidos ships every order with cold-chain packaging to maintain integrity during transit.
Every PT141 order from MiPeptidos includes a batch-specific Certificate of Analysis. Our current batch (HR-PT14-2600315, tested March 27, 2026) shows 99.3% purity by HPLC, mass spectrometry confirmation at 1025.16 Da, endotoxin levels below 0.1 EU/mg, and passing sterility per USP <71>. This level of documentation ensures you can verify compound identity and purity before beginning your research. MiPeptidos also offers bulk pricing on orders of 50+ vials — contact info@mipeptidos.com.

Specifications

Purity
≥99%
Form
Lyophilized Powder
CAS Number
189691-06-3
Mol. Weight
1025.16 Da
Formula
C50H68N14O10
Half-Life
~2.7 hours
Storage
Store at -20°C. Reconstituted: 2–8°C for up to 30 days.
Sizes
10mg

Sequence

Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH (cyclic heptapeptide)

Research Use Only. This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.

Request QuoteBulk Pricing Inquiry

Related Peptides

Melanotan I - MiPeptidos
Ships Today
Sexual Health / Hormonal

Melanotan I

A synthetic analog of alpha-MSH that activates melanocortin receptors. Researched for melanogenesis stimulation and UV-independent tanning pathway studies.

From$34.95/vial
In Stock
≥99%
Melanotan II - MiPeptidos
Ships Today
Sexual Health / Hormonal

Melanotan II

A cyclic melanocortin peptide analog with broader receptor activity than Melanotan I. Studied for melanogenesis, appetite, and sexual function research pathways.

From$34.95/vial
In Stock
≥99%
Kisspeptin-10 - MiPeptidos
Ships Today
Sexual Health / Hormonal

Kisspeptin-10

The decapeptide fragment of kisspeptin, a key regulator of the hypothalamic-pituitary-gonadal axis. Central to reproductive endocrinology and GnRH signaling research.

From$28.95/vial
2 sizesIn Stock
≥99%
Oxytocin Acetate - MiPeptidos
Ships Today
Sexual Health / Hormonal

Oxytocin Acetate

Synthetic form of the naturally occurring neuropeptide oxytocin. Extensively studied for its roles in social bonding, reproductive physiology, and neuroendocrine signaling.

From$11.95/vial
3 sizesIn Stock
≥99%