Kisspeptin-10 - Front - MiPeptidos
Sexual Health / Hormonal

Kisspeptin-10

CAS: 374675-21-5

Kisspeptin-10 is a research peptide in the sexual health / hormonal category. Kisspeptin-10 is the minimal active fragment of the full-length kisspeptin encoded by the KISS1 gene. MiPeptidos offers Kisspeptin-10 in 2 sizes with 99.1% verified purity and full analytical documentation.

Starting at
$28.95/vial
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≥99% Purity
COA Included
Third-Party Tested
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CoA Included
HPLC Verified
GMP Compliant
Third-Party Tested
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How Kisspeptin-10 Works

Kisspeptin-10 is the minimal active fragment of the full-length kisspeptin encoded by the KISS1 gene. It binds to the KISS1R (GPR54) receptor on hypothalamic GnRH neurons, triggering a potent release of gonadotropin-releasing hormone (GnRH). This in turn stimulates pituitary gonadotrophs to release LH and FSH, making kisspeptin the most potent known stimulator of the reproductive endocrine axis. The kisspeptin/GPR54 system serves as the gatekeeper of puberty and fertility.

Research Applications

1
Reproductive endocrinology and fertility
2
Puberty initiation mechanisms
3
GnRH neuron activation and signaling
4
In vitro fertilization (IVF) protocols
5
Hypogonadotropic hypogonadism
View Published Research on PubMed →

Pricing

SizePer Vial10-Pack
5mg
$28.95$210.95
10mgBest Value
$39.95$291.95

Prices shown per vial from 10-pack. Volume discounts available for 50+ vials — contact us.

HPLC Purity Analysis

High-Performance Liquid Chromatography
99.1%purity
mAURetention Time (min)0250500750100005101520253099.1%
Method: RP-HPLC C18 ColumnDetection: UV 220nmMobile Phase: Acetonitrile/Water + 0.1% TFA

Certificate of Analysis

MiPeptidos
Kisspeptin-10
PASSES ALL SPECIFICATIONS
Batch NumberHR-KSSP-2600215
Date of AnalysisFebruary 1, 2026
Purity (HPLC)99.1%
AppearanceWhite to off-white lyophilized powder
SolubilityFreely soluble in sterile water and bacteriostatic water
Molecular Weight (MS)1302.45 Da — Confirmed
Endotoxin (LAL)<0.1 EU/mg
Sterility (USP <71>)Passes USP <71>

This COA is a representative sample. A batch-specific Certificate of Analysis with full HPLC chromatograms and mass spectrometry data is included with every MiPeptidos order.

Reconstitution Calculator

Add this much bacteriostatic water:
5.0 mL
5 mg Kisspeptin-10 + 5.0 mL BAC water = 1 mg/mL

Inject bacteriostatic water slowly along the vial wall. Gently swirl until dissolved — never shake. Store reconstituted solution at 2-8°C and use within 30 days.

Download Product Brochure

Get our detailed Kisspeptin-10 product brochure with specifications, research applications, HPLC analysis data, and reconstitution guide. Available in English and Spanish.

Customer Reviews

5.0/5from 1 review
Verified
Dr. Rebecca Tannenbaum·New York, NY

Kisspeptin-10 from MiPeptidos drives our reproductive neuroendocrinology research. The decapeptide GPR54 agonist shows potent GnRH release in our hypothalamic neuron models. This is the active C-terminal fragment and MiP...

Mar 2, 2026
View All Reviews →

Frequently Asked Questions

Kisspeptin-10 (CAS: 374675-21-5) is a research compound, with a molecular weight of 1302.45 Da in the Sexual Health / Hormonal category. Kisspeptin-10 is the minimal active fragment of the full-length kisspeptin encoded by the KISS1 gene. It binds to the KISS1R (GPR54) receptor on hypothalamic GnRH neurons, triggering a potent release of gonadotropin-releasing hormone (GnRH). Researchers commonly investigate Kisspeptin-10 for Reproductive endocrinology and fertility, Puberty initiation mechanisms, GnRH neuron activation and signaling. Every vial from MiPeptidos includes batch-specific analytical documentation.
Kisspeptin-10 is available in 2 sizes (5mg, 10mg), so reconstitution volume depends on which vial you have. For the 5mg size, add 1-2mL of bacteriostatic water; for the 10mg size, use 2-3mL. Always let the vial warm to room temperature first, inject the water slowly along the vial wall, and swirl gently — never shake. Store reconstituted Kisspeptin-10 at 2-8°C and use within 30 days. MiPeptidos carries bacteriostatic water in 3mL and 10mL vials.
Kisspeptin-10 and Gonadorelin both stimulate GnRH neurons, but at different levels. Kisspeptin-10 acts upstream — it binds the KISS1R (GPR54) receptor on hypothalamic GnRH neurons to trigger GnRH release, which then stimulates LH and FSH. Gonadorelin IS synthetic GnRH (the downstream signal). Kisspeptin-10 is the biologically active C-terminal decapeptide of the full Kisspeptin-54 molecule. MiPeptidos offers both for HPG axis research at different signaling levels.
Store lyophilized Kisspeptin-10 at -20°C for maximum long-term stability — properly stored, it remains potent for 24+ months. Once reconstituted with bacteriostatic water, keep it refrigerated at 2-8°C and use within 30 days. In research applications, Kisspeptin-10 has a reported half-life of ~28 minutes (IV); shorter than full-length kisspeptin, which informs dosing frequency and protocol design. Avoid repeated freeze-thaw cycles and protect from direct light. MiPeptidos ships every order with cold-chain packaging to maintain integrity during transit.
Every Kisspeptin-10 order from MiPeptidos includes a batch-specific Certificate of Analysis. Our current batch (HR-KSSP-2600215, tested February 1, 2026) shows 99.1% purity by HPLC, mass spectrometry confirmation at 1302.45 Da, endotoxin levels below 0.1 EU/mg, and passing sterility per USP <71>. This level of documentation ensures you can verify compound identity and purity before beginning your research. MiPeptidos also offers bulk pricing on orders of 50+ vials — contact info@mipeptidos.com.

Specifications

Purity
≥99%
Form
Lyophilized Powder
CAS Number
374675-21-5
Mol. Weight
1302.45 Da
Formula
C63H83N17O14
Half-Life
~28 minutes (IV); shorter than full-length kisspeptin
Storage
Store at -20°C. Reconstituted: 2–8°C for up to 30 days.
Sizes
5mg, 10mg

Sequence

Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 (decapeptide; C-terminal fragment of kisspeptin)

Research Use Only. This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.

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