Melanotan II - Front - MiPeptidos
Sexual Health / Hormonal

Melanotan II

CAS: 121062-08-6

Melanotan II is a research peptide in the sexual health / hormonal category. Melanotan II is a non-selective cyclic melanocortin receptor agonist that activates MC1R, MC3R, MC4R, and MC5R. MiPeptidos offers Melanotan II in 1 sizes with 99.7% verified purity and full analytical documentation.

Starting at
$34.95/vial
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≥99% Purity
COA Included
Third-Party Tested
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CoA Included
HPLC Verified
GMP Compliant
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How Melanotan II Works

Melanotan II is a non-selective cyclic melanocortin receptor agonist that activates MC1R, MC3R, MC4R, and MC5R. MC1R activation stimulates melanogenesis (tanning), MC3R/MC4R activation in the CNS produces sexual arousal and appetite suppression effects, and MC5R modulation may influence exocrine gland function. Unlike the linear Melanotan I, the cyclic structure provides broader receptor activation, producing simultaneous tanning, sexual arousal, appetite suppression, and fat mobilization.

Research Applications

1
Skin pigmentation and tanning
2
Sexual function and arousal
3
Appetite suppression and feeding behavior
4
Melanocortin receptor pharmacology
5
Body composition effects
View Published Research on PubMed →

Pricing

SizePer Vial10-Pack
10mg
$34.95$254.95

Prices shown per vial from 10-pack. Volume discounts available for 50+ vials — contact us.

HPLC Purity Analysis

High-Performance Liquid Chromatography
99.7%purity
mAURetention Time (min)0250500750100005101520253099.7%
Method: RP-HPLC C18 ColumnDetection: UV 220nmMobile Phase: Acetonitrile/Water + 0.1% TFA

Certificate of Analysis

MiPeptidos
Melanotan II
PASSES ALL SPECIFICATIONS
Batch NumberHR-MLNT-2600115
Date of AnalysisFebruary 15, 2026
Purity (HPLC)99.7%
AppearanceWhite to off-white lyophilized powder
SolubilityFreely soluble in sterile water and bacteriostatic water
Molecular Weight (MS)1024.18 Da — Confirmed
Endotoxin (LAL)<0.1 EU/mg
Sterility (USP <71>)Passes USP <71>

This COA is a representative sample. A batch-specific Certificate of Analysis with full HPLC chromatograms and mass spectrometry data is included with every MiPeptidos order.

Reconstitution Calculator

Add this much bacteriostatic water:
10.0 mL
10 mg Melanotan II + 10.0 mL BAC water = 1 mg/mL

Inject bacteriostatic water slowly along the vial wall. Gently swirl until dissolved — never shake. Store reconstituted solution at 2-8°C and use within 30 days.

Download Product Brochure

Get our detailed Melanotan II product brochure with specifications, research applications, HPLC analysis data, and reconstitution guide. Available in English and Spanish.

Customer Reviews

4.0/5from 1 review
Verified
J.M. Torres·Phoenix, AZ

Melanotan II is our cyclic MSH analog for broad melanocortin receptor research. Purity verified at 98.7%. Four stars because the cyclic lactam bridge is sensitive to storage conditions and I'd suggest MiPeptidos include...

Jan 15, 2026
View All Reviews →

Frequently Asked Questions

Melanotan II (CAS: 121062-08-6) is a research compound, with a molecular weight of 1024.18 Da in the Sexual Health / Hormonal category. Melanotan II is a non-selective cyclic melanocortin receptor agonist that activates MC1R, MC3R, MC4R, and MC5R. MC1R activation stimulates melanogenesis (tanning), MC3R/MC4R activation in the CNS produces sexual arousal and appetite suppression effects, and MC5R modulation may influence exocrine gland function. Researchers commonly investigate Melanotan II for Skin pigmentation and tanning, Sexual function and arousal, Appetite suppression and feeding behavior. Every vial from MiPeptidos includes batch-specific analytical documentation.
To reconstitute your Melanotan II 10mg vial, let it reach room temperature for about 15-20 minutes out of the freezer. Slowly inject 2-3mL of bacteriostatic water along the inside wall of the vial — never aim directly at the peptide cake. Gently swirl until the powder fully dissolves; never shake, as this can denature the peptide. Store reconstituted Melanotan II at 2-8°C and use within 30 days. MiPeptidos includes bacteriostatic water for purchase alongside all peptides.
Melanotan II (1024 Da) is a cyclic heptapeptide that non-selectively activates multiple melanocortin receptors (MC1R through MC5R), producing both melanogenesis (tanning via MC1R) and sexual arousal (via MC4R). It is the parent compound from which PT-141 was derived. Melanotan I is more MC1R-selective (tanning only), while PT-141 is more MC4R-selective (sexual function only). Melanotan II remains popular for combined-effect research. MiPeptidos stocks all three.
Store lyophilized Melanotan II at -20°C for maximum long-term stability — properly stored, it remains potent for 24+ months. Once reconstituted with bacteriostatic water, keep it refrigerated at 2-8°C and use within 30 days. In research applications, Melanotan II has a reported half-life of ~33 minutes, which informs dosing frequency and protocol design. Avoid repeated freeze-thaw cycles and protect from direct light. MiPeptidos ships every order with cold-chain packaging to maintain integrity during transit.
Every Melanotan II order from MiPeptidos includes a batch-specific Certificate of Analysis. Our current batch (HR-MLNT-2600115, tested February 15, 2026) shows 99.7% purity by HPLC, mass spectrometry confirmation at 1024.18 Da, endotoxin levels below 0.1 EU/mg, and passing sterility per USP <71>. This level of documentation ensures you can verify compound identity and purity before beginning your research. MiPeptidos also offers bulk pricing on orders of 50+ vials — contact info@mipeptidos.com.

Specifications

Purity
≥99%
Form
Lyophilized Powder
CAS Number
121062-08-6
Mol. Weight
1024.18 Da
Formula
C50H69N15O9
Half-Life
~33 minutes
Storage
Store at -20°C. Reconstituted: 2–8°C for up to 30 days.
Sizes
10mg

Sequence

Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2 (cyclic heptapeptide)

Research Use Only. This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.

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