Snap-8 - Front - MiPeptidos
Skin / Cosmetic

Snap-8

CAS: 868844-74-0

Snap-8 is a research peptide in the skin / cosmetic category. SNAP-8 is an anti-wrinkle octapeptide that functions by inhibiting the SNARE complex assembly required for neurotransmitter release at the neuromuscular junction. MiPeptidos offers Snap-8 in 2 sizes with 99.4% verified purity and full analytical documentation.

Starting at
$16.95/vial
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≥99% Purity
COA Included
Third-Party Tested
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CoA Included
HPLC Verified
GMP Compliant
Third-Party Tested
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How Snap-8 Works

SNAP-8 is an anti-wrinkle octapeptide that functions by inhibiting the SNARE complex assembly required for neurotransmitter release at the neuromuscular junction. It competes with SNAP-25 (a key SNARE protein) for incorporation into the SNARE complex, reducing acetylcholine release and thereby diminishing muscle contraction intensity. This reduces the depth and appearance of expression lines (similar mechanism to botulinum toxin but through competitive inhibition rather than proteolysis). SNAP-8 is an elongated version of Argireline (hexapeptide) with two additional amino acids for enhanced efficacy.

Research Applications

1
Anti-wrinkle and expression line reduction
2
SNARE complex inhibition pharmacology
3
Non-invasive botulinum toxin alternative
4
Topical peptide skin penetration studies
5
Cosmeceutical formulation development
View Published Research on PubMed →

Pricing

SizePer Vial10-Pack
10mg
$16.95$123.95
100mgBest Value
$28.95$210.95

Prices shown per vial from 10-pack. Volume discounts available for 50+ vials — contact us.

HPLC Purity Analysis

High-Performance Liquid Chromatography
99.4%purity
mAURetention Time (min)0250500750100005101520253099.4%
Method: RP-HPLC C18 ColumnDetection: UV 220nmMobile Phase: Acetonitrile/Water + 0.1% TFA

Certificate of Analysis

MiPeptidos
Snap-8
PASSES ALL SPECIFICATIONS
Batch NumberHR-SNP8-2600115
Date of AnalysisMarch 16, 2026
Purity (HPLC)99.4%
AppearanceWhite to off-white lyophilized powder
SolubilityFreely soluble in sterile water and bacteriostatic water
Molecular Weight (MS)1075.16 Da — Confirmed
Endotoxin (LAL)<0.1 EU/mg
Sterility (USP <71>)Passes USP <71>

This COA is a representative sample. A batch-specific Certificate of Analysis with full HPLC chromatograms and mass spectrometry data is included with every MiPeptidos order.

Reconstitution Calculator

Add this much bacteriostatic water:
10.0 mL
10 mg Snap-8 + 10.0 mL BAC water = 1 mg/mL

Inject bacteriostatic water slowly along the vial wall. Gently swirl until dissolved — never shake. Store reconstituted solution at 2-8°C and use within 30 days.

Download Product Brochure

Get our detailed Snap-8 product brochure with specifications, research applications, HPLC analysis data, and reconstitution guide. Available in English and Spanish.

Customer Reviews

5.0/5from 1 review
Verified
Christina Alexopoulos·Athens, Greece

SNAP-8 (acetyl octapeptide-3) from MiPeptidos is a SNARE complex modulator we use in our neuromuscular junction research. The octapeptide shows dose-dependent inhibition of catecholamine release in our chromaffin cell mo...

Dec 10, 2025
View All Reviews →

Frequently Asked Questions

Snap-8 (CAS: 868844-74-0) is a research compound, with a molecular weight of 1075.16 Da in the Skin / Cosmetic category. SNAP-8 is an anti-wrinkle octapeptide that functions by inhibiting the SNARE complex assembly required for neurotransmitter release at the neuromuscular junction. It competes with SNAP-25 (a key SNARE protein) for incorporation into the SNARE complex, reducing acetylcholine release and thereby diminishing muscle contraction intensity. Researchers commonly investigate Snap-8 for Anti-wrinkle and expression line reduction, SNARE complex inhibition pharmacology, Non-invasive botulinum toxin alternative. Every vial from MiPeptidos includes batch-specific analytical documentation.
Snap-8 is available in 2 sizes (10mg, 100mg), so reconstitution volume depends on which vial you have. For the 10mg size, add 2-3mL of bacteriostatic water; for the 100mg size, use 6-8mL. Always let the vial warm to room temperature first, inject the water slowly along the vial wall, and swirl gently — never shake. Store reconstituted Snap-8 at 2-8°C and use within 30 days. MiPeptidos carries bacteriostatic water in 3mL and 10mL vials.
Snap-8 and Matrixyl are both cosmetic peptides, but they work through completely different mechanisms. Snap-8 (1075 Da) is an octapeptide that mimics the N-terminal domain of SNAP-25 protein, competitively inhibiting SNARE complex formation to reduce acetylcholine release at neuromuscular junctions — essentially a topical mechanism similar to botulinum toxin. Matrixyl (802 Da) stimulates collagen synthesis via the TIMP-1 pathway. MiPeptidos carries both for skin biology research.
Store lyophilized Snap-8 at -20°C for maximum long-term stability — properly stored, it remains potent for 24+ months. Once reconstituted with bacteriostatic water, keep it refrigerated at 2-8°C and use within 30 days. In research applications, Snap-8 has a reported half-life of Topical application; not relevant in systemic terms. Effects are local and cumulative., which informs dosing frequency and protocol design. Avoid repeated freeze-thaw cycles and protect from direct light. MiPeptidos ships every order with cold-chain packaging to maintain integrity during transit.
Every Snap-8 order from MiPeptidos includes a batch-specific Certificate of Analysis. Our current batch (HR-SNP8-2600115, tested March 16, 2026) shows 99.4% purity by HPLC, mass spectrometry confirmation at 1075.16 Da, endotoxin levels below 0.1 EU/mg, and passing sterility per USP <71>. This level of documentation ensures you can verify compound identity and purity before beginning your research. MiPeptidos also offers bulk pricing on orders of 50+ vials — contact info@mipeptidos.com.

Specifications

Purity
≥99%
Form
Lyophilized Powder
CAS Number
868844-74-0
Mol. Weight
1075.16 Da
Formula
C41H70N16O16S
Half-Life
Topical application; not relevant in systemic terms. Effects are local and cumulative.
Storage
Store at -20°C. Reconstituted: 2–8°C for up to 30 days.
Sizes
10mg, 100mg

Sequence

Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2 (octapeptide; extension of Argireline)

Research Use Only. This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.

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