B7-33 - Front - MiPeptidos
Skin / Cosmetic

B7-33

CAS: 1818415-56-3

B7-33 is a research peptide in the skin / cosmetic category. B7-33 is a single-chain peptide agonist of relaxin family peptide receptor 1 (RXFP1) derived from the B-chain of human relaxin-2. MiPeptidos offers B7-33 in 2 sizes with 99.1% verified purity and full analytical documentation.

Starting at
$22.95/vial
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≥99% Purity
COA Included
Third-Party Tested
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CoA Included
HPLC Verified
GMP Compliant
Third-Party Tested
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How B7-33 Works

B7-33 is a single-chain peptide agonist of relaxin family peptide receptor 1 (RXFP1) derived from the B-chain of human relaxin-2. Unlike native relaxin (which requires a two-chain A-B structure), B7-33 consists solely of the B-chain with modifications that enable RXFP1 binding and activation. It selectively activates anti-fibrotic signaling pathways (pERK1/2) through RXFP1 without activating the cAMP pathway, making it a biased agonist. This promotes collagen remodeling, reduces fibrosis, and enhances wound healing.

Research Applications

1
Anti-fibrotic therapy (cardiac, pulmonary, hepatic)
2
Wound healing and scar reduction
3
RXFP1 biased agonism
4
Skin rejuvenation and collagen remodeling
5
Cardiovascular remodeling after myocardial infarction
View Published Research on PubMed →

Pricing

SizePer Vial10-Pack
2mg
$22.95$167.95
10mgBest Value
$86.95$634.95

Prices shown per vial from 10-pack. Volume discounts available for 50+ vials — contact us.

HPLC Purity Analysis

High-Performance Liquid Chromatography
99.1%purity
mAURetention Time (min)0250500750100005101520253099.1%
Method: RP-HPLC C18 ColumnDetection: UV 220nmMobile Phase: Acetonitrile/Water + 0.1% TFA

Certificate of Analysis

MiPeptidos
B7-33
PASSES ALL SPECIFICATIONS
Batch NumberHR-B733-2600315
Date of AnalysisFebruary 9, 2026
Purity (HPLC)99.1%
AppearanceWhite to off-white lyophilized powder
SolubilityFreely soluble in sterile water and bacteriostatic water
Molecular Weight (MS)2987.75 Da — Confirmed
Endotoxin (LAL)<0.1 EU/mg
Sterility (USP <71>)Passes USP <71>

This COA is a representative sample. A batch-specific Certificate of Analysis with full HPLC chromatograms and mass spectrometry data is included with every MiPeptidos order.

Reconstitution Calculator

Add this much bacteriostatic water:
2.0 mL
2 mg B7-33 + 2.0 mL BAC water = 1 mg/mL

Inject bacteriostatic water slowly along the vial wall. Gently swirl until dissolved — never shake. Store reconstituted solution at 2-8°C and use within 30 days.

Download Product Brochure

Get our detailed B7-33 product brochure with specifications, research applications, HPLC analysis data, and reconstitution guide. Available in English and Spanish.

Customer Reviews

5.0/5from 1 review
Verified
Dr. Aisha Khan·Karachi, Pakistan

B7-33 is a single-chain relaxin mimetic peptide vital for our cardiovascular and fibrosis research. MiPeptidos' product activates RXFP1 receptors in our cardiac fibroblast models with the expected anti-fibrotic signaling...

Feb 7, 2026
View All Reviews →

Frequently Asked Questions

B7-33 (CAS: 1818415-56-3) is a research compound, with a molecular weight of 2987.75 Da in the Skin / Cosmetic category. B7-33 is a single-chain peptide agonist of relaxin family peptide receptor 1 (RXFP1) derived from the B-chain of human relaxin-2. Unlike native relaxin (which requires a two-chain A-B structure), B7-33 consists solely of the B-chain with modifications that enable RXFP1 binding and activation. Researchers commonly investigate B7-33 for Anti-fibrotic therapy (cardiac, pulmonary, hepatic), Wound healing and scar reduction, RXFP1 biased agonism. Every vial from MiPeptidos includes batch-specific analytical documentation.
B7-33 is available in 2 sizes (2mg, 10mg), so reconstitution volume depends on which vial you have. For the 2mg size, add 1mL of bacteriostatic water; for the 10mg size, use 2-3mL. Always let the vial warm to room temperature first, inject the water slowly along the vial wall, and swirl gently — never shake. Store reconstituted B7-33 at 2-8°C and use within 30 days. MiPeptidos carries bacteriostatic water in 3mL and 10mL vials.
B7-33 is a simplified single-chain 33-amino acid peptide (2988 Da) that selectively activates the RXFP1 relaxin receptor, mimicking the antifibrotic and vasodilatory effects of the full heterodimeric relaxin-2 hormone without requiring the complex two-chain structure. Native relaxin-2 is difficult to manufacture due to its A/B chain disulfide linkages. B7-33 was designed to replicate the B-chain receptor binding site in a single chain. MiPeptidos offers this for fibrosis and cardiovascular research.
Store lyophilized B7-33 at -20°C for maximum long-term stability — properly stored, it remains potent for 24+ months. Once reconstituted with bacteriostatic water, keep it refrigerated at 2-8°C and use within 30 days. In research applications, B7-33 has a reported half-life of Not fully characterized; single-chain structure may have shorter half-life than native relaxin, which informs dosing frequency and protocol design. Avoid repeated freeze-thaw cycles and protect from direct light. MiPeptidos ships every order with cold-chain packaging to maintain integrity during transit.
Every B7-33 order from MiPeptidos includes a batch-specific Certificate of Analysis. Our current batch (HR-B733-2600315, tested February 9, 2026) shows 99.1% purity by HPLC, mass spectrometry confirmation at 2987.75 Da, endotoxin levels below 0.1 EU/mg, and passing sterility per USP <71>. This level of documentation ensures you can verify compound identity and purity before beginning your research. MiPeptidos also offers bulk pricing on orders of 50+ vials — contact info@mipeptidos.com.

Specifications

Purity
≥99%
Form
Lyophilized Powder
CAS Number
1818415-56-3
Mol. Weight
2987.75 Da
Formula
C131H228N40O37S
Half-Life
Not fully characterized; single-chain structure may have shorter half-life than native relaxin
Storage
Store at -20°C. Reconstituted: 2–8°C for up to 30 days.
Sizes
2mg, 10mg

Sequence

VIKLSGRELVRAQIAISGMSTWSKRSL (26 amino acids; single-chain relaxin B-chain analog)

Research Use Only. This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.

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