Semaglutide - Front - MiPeptidos
GLP-1 / Weight Management

Semaglutide

CAS: 910463-68-2

Semaglutide is a research peptide in the glp-1 / weight management category. Semaglutide is a GLP-1 receptor agonist that mimics native GLP-1 to stimulate insulin secretion in a glucose-dependent manner while suppressing glucagon release. MiPeptidos offers Semaglutide in 6 sizes with 99.1% verified purity and full analytical documentation.

Starting at
$14.95/vial
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≥99% Purity
COA Included
Third-Party Tested
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CoA Included
HPLC Verified
GMP Compliant
Third-Party Tested
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Batch Tracked

How Semaglutide Works

Semaglutide is a GLP-1 receptor agonist that mimics native GLP-1 to stimulate insulin secretion in a glucose-dependent manner while suppressing glucagon release. The Aib substitution at position 2 confers resistance to DPP-IV enzymatic degradation, and the C18 fatty diacid chain enables high-affinity albumin binding, extending its half-life substantially. It also acts on hypothalamic appetite centers to reduce food intake and delay gastric emptying.

Research Applications

1
Type 2 diabetes glycemic control
2
Obesity and weight management
3
Cardiovascular risk reduction in diabetic populations
4
Non-alcoholic steatohepatitis (NASH) / fatty liver disease
5
Appetite regulation and satiety signaling pathways
View Published Research on PubMed →

Pricing

SizePer Vial10-Pack
2mg
$14.95$108.95
5mg
$31.95$232.95
10mg
$46.95$342.95
15mg
$64.95$473.95
20mg
$82.95$605.95
50mgBest Value
$174.95$1276.95

Prices shown per vial from 10-pack. Volume discounts available for 50+ vials — contact us.

HPLC Purity Analysis

High-Performance Liquid Chromatography
99.1%purity
mAURetention Time (min)0250500750100005101520253099.1%
Method: RP-HPLC C18 ColumnDetection: UV 220nmMobile Phase: Acetonitrile/Water + 0.1% TFA

Certificate of Analysis

MiPeptidos
Semaglutide
PASSES ALL SPECIFICATIONS
Batch NumberHR-SMGL-2600315
Date of AnalysisJanuary 21, 2026
Purity (HPLC)99.1%
AppearanceWhite to off-white lyophilized powder
SolubilityFreely soluble in sterile water and bacteriostatic water
Molecular Weight (MS)4113.64 Da — Confirmed
Endotoxin (LAL)<0.1 EU/mg
Sterility (USP <71>)Passes USP <71>

This COA is a representative sample. A batch-specific Certificate of Analysis with full HPLC chromatograms and mass spectrometry data is included with every MiPeptidos order.

Reconstitution Calculator

Add this much bacteriostatic water:
2.0 mL
2 mg Semaglutide + 2.0 mL BAC water = 1 mg/mL

Inject bacteriostatic water slowly along the vial wall. Gently swirl until dissolved — never shake. Store reconstituted solution at 2-8°C and use within 30 days.

Download Product Brochure

Get our detailed Semaglutide product brochure with specifications, research applications, HPLC analysis data, and reconstitution guide. Available in English and Spanish.

Researcher Reviews

4.7/5from 3 reviews
Verified
Dr. Marcus Whitfield·Houston, TX

We've been sourcing semaglutide from MiPeptidos for six months and consistency is remarkable. Every batch arrives with a full COA and HPLC-verified purity consistently exceeds 99%. Cold-chain shipping intact on arrival....

Feb 18, 2026
Verified
Ayumi T.·Tokyo, Japan

Ordered the 10mg semaglutide vials for our university GLP-1 receptor binding assays. Lyophilized powder reconstituted cleanly and our independent mass spec results matched the COA. International shipping to Japan took ab...

Jan 30, 2026
Verified
Isabella Reyes-Moreno·Guadalajara, Mexico

La pureza del semaglutide is excellent, confirmed at 99.1% via our own HPLC. Four stars only because the website checkout could be smoother on mobile for international orders. Product quality itself is outstanding and we...

Dec 14, 2025
View All Reviews →

Frequently Asked Questions

Semaglutide (CAS: 910463-68-2) is a research compound, with a molecular weight of 4113.64 Da in the GLP-1 / Weight Management category. Semaglutide is a GLP-1 receptor agonist that mimics native GLP-1 to stimulate insulin secretion in a glucose-dependent manner while suppressing glucagon release. The Aib substitution at position 2 confers resistance to DPP-IV enzymatic degradation, and the C18 fatty diacid chain enables high-affinity albumin binding, extending its half-life substantially. Researchers commonly investigate Semaglutide for Type 2 diabetes glycemic control, Obesity and weight management, Cardiovascular risk reduction in diabetic populations. Every vial from MiPeptidos includes batch-specific analytical documentation.
Semaglutide is available in 6 sizes (2mg, 5mg, 10mg, 15mg, 20mg, 50mg), so reconstitution volume depends on which vial you have. For the 2mg size, add 1mL of bacteriostatic water; for the 50mg size, use 5-6mL. Always let the vial warm to room temperature first, inject the water slowly along the vial wall, and swirl gently — never shake. Store reconstituted Semaglutide at 2-8°C and use within 30 days. MiPeptidos carries bacteriostatic water in 3mL and 10mL vials.
Semaglutide is a pure GLP-1 receptor agonist, while Tirzepatide is a dual GIP/GLP-1 agonist. Semaglutide has a longer half-life (~7 days vs ~5 days) thanks to its C18 fatty diacid-albumin binding mechanism, but Tirzepatide activates two incretin pathways simultaneously, which some Phase 3 trials suggest produces greater weight reduction. Semaglutide also has more extensive published cardiovascular outcome data (SELECT trial). MiPeptidos stocks both in multiple sizes so researchers can design head-to-head protocols.
Store lyophilized Semaglutide at -20°C for maximum long-term stability — properly stored, it remains potent for 24+ months. Once reconstituted with bacteriostatic water, keep it refrigerated at 2-8°C and use within 30 days. In research applications, Semaglutide has a reported half-life of ~7 days (enabling once-weekly dosing), which informs dosing frequency and protocol design. Avoid repeated freeze-thaw cycles and protect from direct light. MiPeptidos ships every order with cold-chain packaging to maintain integrity during transit.
Every Semaglutide order from MiPeptidos includes a batch-specific Certificate of Analysis. Our current batch (HR-SMGL-2600315, tested January 21, 2026) shows 99.1% purity by HPLC, mass spectrometry confirmation at 4113.64 Da, endotoxin levels below 0.1 EU/mg, and passing sterility per USP <71>. This level of documentation ensures you can verify compound identity and purity before beginning your research. MiPeptidos also offers bulk pricing on orders of 50+ vials — contact info@mipeptidos.com.

Specifications

Purity
≥99%
Form
Lyophilized Powder
CAS Number
910463-68-2
Mol. Weight
4113.64 Da
Formula
C187H291N45O59
Half-Life
~7 days (enabling once-weekly dosing)
Storage
Store at -20°C. Reconstituted: 2–8°C for up to 30 days.
Sizes
2mg, 5mg, 10mg, 15mg, 20mg, 50mg

Sequence

Modified GLP-1(7-37) analog; 31 amino acids with Aib at position 8, Arg at position 34, and a C18 fatty diacid chain via linker at Lys26

Research Use Only. This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.

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