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P21 (P021) - Front - MiPeptidos
Cognitive / Neuropeptides

P21 (P021)

CAS: Not assigned

Alzheimer's disease and tau pathology · Hippocampal neurogenesis stimulation · BDNF upregulation via novel pathway

P21 is a synthetic peptide derived from a short epitope (residues 148-151) of ciliary neurotrophic factor (CNTF) with an adamantane moiety appended for blood-brain barrier penetration and oral bioavailability.

  • Alzheimer's disease and tau pathology
  • Hippocampal neurogenesis stimulation
  • BDNF upregulation via novel pathway
  • Oral nootropic peptide design
Research Use Only.

This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.

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$240.00/vial
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≥99% HPLC| COA Included| Ships Today
≥99% Purity
COA Included
Third-Party Tested
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P21 (P021) Brochure
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HPLC Purity Analysis

High-Performance Liquid Chromatography
99.8%purity
mAURetention Time (min)0250500750100005101520253099.8%
Method: RP-HPLC C18UV 220nmACN/H₂O + 0.1% TFA
CoA Included
HPLC Verified
GMP Compliant
Third-Party Tested
Same-Day Shipping
Batch Tracked

Specifications

Purity
≥99%
Form
Lyophilized Powder
CAS
Not assigned
Mol. Weight
578.30 Da

How P21 (P021) Works

P21 is a synthetic peptide derived from a short epitope (residues 148-151) of ciliary neurotrophic factor (CNTF) with an adamantane moiety appended for blood-brain barrier penetration and oral bioavailability. It enhances BDNF expression by inhibiting leukemia inhibitory factor (LIF) signaling, promotes dentate gyrus neurogenesis, inhibits GSK-3beta activity (reducing tau phosphorylation), and provides neuroprotection without the adverse effects associated with full-length CNTF administration.

Research Applications

1
Alzheimer's disease and tau pathology
2
Hippocampal neurogenesis stimulation
3
BDNF upregulation via novel pathway
4
Oral nootropic peptide design
5
Cognitive enhancement in aging models

Pricing

SizePer Vial10-Pack
5mg
$240.00$2400.00

10-pack pricing shown. Volume discounts for 50+ vials — contact us.

Certificate of Analysis

MiPeptidos
P21 (P021)
PASSES ALL SPECIFICATIONS
Batch NumberHR-P21P-2600115
Date of AnalysisFebruary 4, 2026
Purity (HPLC)99.8%
AppearanceWhite to off-white lyophilized powder
SolubilityFreely soluble in sterile water and bacteriostatic water
Molecular Weight (MS)578.30 Da — Confirmed
Endotoxin (LAL)<0.1 EU/mg
Sterility (USP <71>)Passes USP <71>

This COA is a representative sample. A batch-specific Certificate of Analysis with full HPLC chromatograms and mass spectrometry data is included with every order.

Research Use Only. This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.