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Orexin A - Front - MiPeptidos
Cognitive / Neuropeptides

Orexin A

CAS: 205640-90-0

Narcolepsy and sleep-wake disorders · Wakefulness and arousal mechanisms · Appetite and feeding behavior regulation

Orexin A is a neuropeptide produced by hypothalamic orexin neurons that binds with high affinity to both OX1R and OX2R receptors.

  • Narcolepsy and sleep-wake disorders
  • Wakefulness and arousal mechanisms
  • Appetite and feeding behavior regulation
  • Reward circuitry and addiction research
Research Use Only.

This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.

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≥99% HPLC| COA Included| Ships Today
≥99% Purity
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HPLC Purity Analysis

High-Performance Liquid Chromatography
99.2%purity
mAURetention Time (min)0250500750100005101520253099.2%
Method: RP-HPLC C18UV 220nmACN/H₂O + 0.1% TFA
CoA Included
HPLC Verified
GMP Compliant
Third-Party Tested
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Batch Tracked

Specifications

Purity
≥99%
Form
Lyophilized Powder
CAS
205640-90-0
Mol. Weight
3561.19 Da

How Orexin A Works

Orexin A is a neuropeptide produced by hypothalamic orexin neurons that binds with high affinity to both OX1R and OX2R receptors. It is the primary regulator of wakefulness, arousal, and the sleep-wake cycle. Orexin A promotes alertness by exciting monoaminergic and cholinergic neurons in the brainstem arousal centers, stimulates feeding behavior, increases metabolic rate, and regulates reward-motivated behavior. Loss of orexin neurons causes narcolepsy type 1 with cataplexy.

Research Applications

1
Narcolepsy and sleep-wake disorders
2
Wakefulness and arousal mechanisms
3
Appetite and feeding behavior regulation
4
Reward circuitry and addiction research
5
Cognitive alertness enhancement

Pricing

SizePer Vial10-Pack
10mg
$400.00$4000.00

10-pack pricing shown. Volume discounts for 50+ vials — contact us.

Certificate of Analysis

MiPeptidos
Orexin A
PASSES ALL SPECIFICATIONS
Batch NumberHR-RXN-2600315
Date of AnalysisMarch 18, 2026
Purity (HPLC)99.2%
AppearanceWhite to off-white lyophilized powder
SolubilityFreely soluble in sterile water and bacteriostatic water
Molecular Weight (MS)3561.19 Da — Confirmed
Endotoxin (LAL)<0.1 EU/mg
Sterility (USP <71>)Passes USP <71>

This COA is a representative sample. A batch-specific Certificate of Analysis with full HPLC chromatograms and mass spectrometry data is included with every order.

Research Use Only. This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.