KPV - Front - MiPeptidos
Healing / Recovery

KPV

CAS: 67727-97-3

KPV is a research peptide in the healing / recovery category. KPV is a C-terminal tripeptide fragment of alpha-melanocyte stimulating hormone (alpha-MSH). MiPeptidos offers KPV in 2 sizes with 99.2% verified purity and full analytical documentation.

Starting at
$22.95/vial
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≥99% Purity
COA Included
Third-Party Tested
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CoA Included
HPLC Verified
GMP Compliant
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How KPV Works

KPV is a C-terminal tripeptide fragment of alpha-melanocyte stimulating hormone (alpha-MSH). It exerts potent anti-inflammatory effects by inhibiting NF-kB activation, suppressing pro-inflammatory cytokine production (TNF-alpha, IL-6, IL-1beta), and entering cells to directly interact with inflammatory signaling cascades in the nucleus. Unlike full alpha-MSH, KPV does not bind melanocortin receptors and has no melanogenic activity, making its anti-inflammatory effects receptor-independent and intracellular.

Research Applications

1
Inflammatory bowel disease (IBD) and colitis
2
Gut inflammation and mucosal healing
3
Skin inflammation and dermatitis
4
NF-kB pathway inhibition studies
5
Anti-inflammatory peptide therapeutics
View Published Research on PubMed →

Pricing

SizePer Vial10-Pack
5mg
$22.95$167.95
10mgBest Value
$24.95$181.95

Prices shown per vial from 10-pack. Volume discounts available for 50+ vials — contact us.

HPLC Purity Analysis

High-Performance Liquid Chromatography
99.2%purity
mAURetention Time (min)0250500750100005101520253099.2%
Method: RP-HPLC C18 ColumnDetection: UV 220nmMobile Phase: Acetonitrile/Water + 0.1% TFA

Certificate of Analysis

MiPeptidos
KPV
PASSES ALL SPECIFICATIONS
Batch NumberHR-KPV-2600115
Date of AnalysisJanuary 18, 2026
Purity (HPLC)99.2%
AppearanceWhite to off-white lyophilized powder
SolubilityFreely soluble in sterile water and bacteriostatic water
Molecular Weight (MS)342.43 Da — Confirmed
Endotoxin (LAL)<0.1 EU/mg
Sterility (USP <71>)Passes USP <71>

This COA is a representative sample. A batch-specific Certificate of Analysis with full HPLC chromatograms and mass spectrometry data is included with every MiPeptidos order.

Reconstitution Calculator

Add this much bacteriostatic water:
5.0 mL
5 mg KPV + 5.0 mL BAC water = 1 mg/mL

Inject bacteriostatic water slowly along the vial wall. Gently swirl until dissolved — never shake. Store reconstituted solution at 2-8°C and use within 30 days.

Download Product Brochure

Get our detailed KPV product brochure with specifications, research applications, HPLC analysis data, and reconstitution guide. Available in English and Spanish.

Customer Reviews

5.0/5from 1 review
Verified
Daniela Ferreira·Sao Paulo, Brazil

KPV tripeptide from MiPeptidos showed potent anti-inflammatory activity in our NF-kB pathway studies. This alpha-MSH derivative is only three amino acids but the purity matters enormously at this scale, and MiPeptidos de...

Jan 25, 2026
View All Reviews →

Frequently Asked Questions

KPV (CAS: 67727-97-3) is a research compound, with a molecular weight of 342.43 Da in the Healing / Recovery category. KPV is a C-terminal tripeptide fragment of alpha-melanocyte stimulating hormone (alpha-MSH). It exerts potent anti-inflammatory effects by inhibiting NF-kB activation, suppressing pro-inflammatory cytokine production (TNF-alpha, IL-6, IL-1beta), and entering cells to directly interact with inflammatory signaling cascades in the nucleus. Researchers commonly investigate KPV for Inflammatory bowel disease (IBD) and colitis, Gut inflammation and mucosal healing, Skin inflammation and dermatitis. Every vial from MiPeptidos includes batch-specific analytical documentation.
KPV is available in 2 sizes (5mg, 10mg), so reconstitution volume depends on which vial you have. For the 5mg size, add 1-2mL of bacteriostatic water; for the 10mg size, use 2-3mL. Always let the vial warm to room temperature first, inject the water slowly along the vial wall, and swirl gently — never shake. Store reconstituted KPV at 2-8°C and use within 30 days. MiPeptidos carries bacteriostatic water in 3mL and 10mL vials.
KPV and BPC-157 both have anti-inflammatory properties, but KPV is a tripeptide (Lys-Pro-Val, just 342 Da) derived from alpha-MSH that specifically inhibits NF-kB nuclear translocation and IL-1beta/TNF-alpha production. BPC-157 is a larger pentadecapeptide (1420 Da) focused on tissue repair via angiogenesis. KPV is particularly studied for gut inflammation (IBD models) due to its small size allowing mucosal absorption. MiPeptidos offers both for inflammation and healing research.
Store lyophilized KPV at -20°C for maximum long-term stability — properly stored, it remains potent for 24+ months. Once reconstituted with bacteriostatic water, keep it refrigerated at 2-8°C and use within 30 days. In research applications, KPV has a reported half-life of Short; estimated minutes to hours, which informs dosing frequency and protocol design. Avoid repeated freeze-thaw cycles and protect from direct light. MiPeptidos ships every order with cold-chain packaging to maintain integrity during transit.
Every KPV order from MiPeptidos includes a batch-specific Certificate of Analysis. Our current batch (HR-KPV-2600115, tested January 18, 2026) shows 99.2% purity by HPLC, mass spectrometry confirmation at 342.43 Da, endotoxin levels below 0.1 EU/mg, and passing sterility per USP <71>. This level of documentation ensures you can verify compound identity and purity before beginning your research. MiPeptidos also offers bulk pricing on orders of 50+ vials — contact info@mipeptidos.com.

Specifications

Purity
≥99%
Form
Lyophilized Powder
CAS Number
67727-97-3
Mol. Weight
342.43 Da
Formula
C16H30N4O4
Half-Life
Short; estimated minutes to hours
Storage
Store at -20°C. Reconstituted: 2–8°C for up to 30 days.
Sizes
5mg, 10mg

Sequence

Lys-Pro-Val (tripeptide; C-terminal fragment of alpha-MSH)

Research Use Only. This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.

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