Sermorelin Acetate - Front - MiPeptidos
Growth Hormone / GH Secretagogues

Sermorelin Acetate

CAS: 86168-78-7

Sermorelin Acetate is a research peptide in the growth hormone / gh secretagogues category. Sermorelin is a synthetic 29-amino acid peptide corresponding to the first 29 amino acids of endogenous GHRH, which represents the minimally active fragment required for full biological activity. MiPeptidos offers Sermorelin Acetate in 3 sizes with 99.1% verified purity and full analytical documentation.

Starting at
$12.95/vial
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≥99% Purity
COA Included
Third-Party Tested
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CoA Included
HPLC Verified
GMP Compliant
Third-Party Tested
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How Sermorelin Acetate Works

Sermorelin is a synthetic 29-amino acid peptide corresponding to the first 29 amino acids of endogenous GHRH, which represents the minimally active fragment required for full biological activity. It binds to GHRH receptors on pituitary somatotrophs, activating adenylyl cyclase via Gs proteins to increase cAMP and stimulate GH gene transcription, synthesis, and pulsatile release. It preserves the natural GH feedback axis and promotes slow-wave sleep-associated GH secretion.

Research Applications

1
GH deficiency treatment (FDA-approved diagnostic)
2
Anti-aging and GH optimization
3
Sleep quality improvement
4
Pituitary function assessment
5
Pediatric growth hormone stimulation testing
View Published Research on PubMed →

Pricing

SizePer Vial10-Pack
2mg
$12.95$94.95
5mg
$24.95$181.95
10mgBest Value
$42.95$313.95

Prices shown per vial from 10-pack. Volume discounts available for 50+ vials — contact us.

HPLC Purity Analysis

High-Performance Liquid Chromatography
99.1%purity
mAURetention Time (min)0250500750100005101520253099.1%
Method: RP-HPLC C18 ColumnDetection: UV 220nmMobile Phase: Acetonitrile/Water + 0.1% TFA

Certificate of Analysis

MiPeptidos
Sermorelin Acetate
PASSES ALL SPECIFICATIONS
Batch NumberHR-SRMR-2600115
Date of AnalysisFebruary 13, 2026
Purity (HPLC)99.1%
AppearanceWhite to off-white lyophilized powder
SolubilityFreely soluble in sterile water and bacteriostatic water
Molecular Weight (MS)3357.90 Da — Confirmed
Endotoxin (LAL)<0.1 EU/mg
Sterility (USP <71>)Passes USP <71>

This COA is a representative sample. A batch-specific Certificate of Analysis with full HPLC chromatograms and mass spectrometry data is included with every MiPeptidos order.

Reconstitution Calculator

Add this much bacteriostatic water:
2.0 mL
2 mg Sermorelin Acetate + 2.0 mL BAC water = 1 mg/mL

Inject bacteriostatic water slowly along the vial wall. Gently swirl until dissolved — never shake. Store reconstituted solution at 2-8°C and use within 30 days.

Download Product Brochure

Get our detailed Sermorelin Acetate product brochure with specifications, research applications, HPLC analysis data, and reconstitution guide. Available in English and Spanish.

Customer Reviews

5.0/5from 1 review
Verified
Karen Mitchell·Scottsdale, AZ

Sermorelin acetate is our primary GHRH analog for age-related GH decline research. MiPeptidos' 29-amino-acid peptide maintains the critical 1-29 fragment bioactivity with 99.1% HPLC purity. Reconstitutes beautifully and...

Jan 8, 2026
View All Reviews →

Frequently Asked Questions

Sermorelin Acetate (CAS: 86168-78-7) is a research compound, with a molecular weight of 3357.90 Da in the Growth Hormone / GH Secretagogues category. Sermorelin is a synthetic 29-amino acid peptide corresponding to the first 29 amino acids of endogenous GHRH, which represents the minimally active fragment required for full biological activity. It binds to GHRH receptors on pituitary somatotrophs, activating adenylyl cyclase via Gs proteins to increase cAMP and stimulate GH gene transcription, synthesis, and pulsatile release. Researchers commonly investigate Sermorelin Acetate for GH deficiency treatment (FDA-approved diagnostic), Anti-aging and GH optimization, Sleep quality improvement. Every vial from MiPeptidos includes batch-specific analytical documentation.
Sermorelin Acetate is available in 3 sizes (2mg, 5mg, 10mg), so reconstitution volume depends on which vial you have. For the 2mg size, add 1mL of bacteriostatic water; for the 10mg size, use 2-3mL. Always let the vial warm to room temperature first, inject the water slowly along the vial wall, and swirl gently — never shake. Store reconstituted Sermorelin Acetate at 2-8°C and use within 30 days. MiPeptidos carries bacteriostatic water in 3mL and 10mL vials.
Sermorelin and CJC-1295 (without DAC) are both GHRH analogs, but Sermorelin contains the first 29 amino acids of native GHRH (3358 Da) while CJC-1295 has four amino acid substitutions that improve DPP-IV resistance, extending its half-life from ~10 minutes (Sermorelin) to ~30 minutes. Sermorelin is FDA-approved for diagnostic use, giving it a stronger clinical pedigree. MiPeptidos offers both for researchers comparing native-sequence vs stabilized GHRH analogs.
Store lyophilized Sermorelin Acetate at -20°C for maximum long-term stability — properly stored, it remains potent for 24+ months. Once reconstituted with bacteriostatic water, keep it refrigerated at 2-8°C and use within 30 days. In research applications, Sermorelin Acetate has a reported half-life of ~10-20 minutes, which informs dosing frequency and protocol design. Avoid repeated freeze-thaw cycles and protect from direct light. MiPeptidos ships every order with cold-chain packaging to maintain integrity during transit.
Every Sermorelin Acetate order from MiPeptidos includes a batch-specific Certificate of Analysis. Our current batch (HR-SRMR-2600115, tested February 13, 2026) shows 99.1% purity by HPLC, mass spectrometry confirmation at 3357.90 Da, endotoxin levels below 0.1 EU/mg, and passing sterility per USP <71>. This level of documentation ensures you can verify compound identity and purity before beginning your research. MiPeptidos also offers bulk pricing on orders of 50+ vials — contact info@mipeptidos.com.

Specifications

Purity
≥99%
Form
Lyophilized Powder
CAS Number
86168-78-7
Mol. Weight
3357.90 Da
Formula
C149H246N44O42S
Half-Life
~10-20 minutes
Storage
Store at -20°C. Reconstituted: 2–8°C for up to 30 days.
Sizes
2mg, 5mg, 10mg

Sequence

Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2 (29 amino acids)

Research Use Only. This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.

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