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Growth Hormone / GH Secretagogues

MK677

CAS: 159634-47-6

Oral GH secretagogue pharmacology · Muscle wasting and sarcopenia · Bone density improvement

MK-677 is an orally active, non-peptidic ghrelin receptor (GHSR-1a) agonist that mimics the GH-releasing activity of ghrelin.

  • Oral GH secretagogue pharmacology
  • Muscle wasting and sarcopenia
  • Bone density improvement
  • Sleep quality and GH pulse enhancement
Research Use Only.

This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.

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Bacteriostatic Water

Bacteriostatic Water

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HGH

HGH

Growth Hormone / GH Secretagogues

$50.00
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≥99% HPLC| COA Included| Ships Today
≥99% Purity
COA Included
Third-Party Tested
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HPLC Purity Analysis

High-Performance Liquid Chromatography
99.1%purity
mAURetention Time (min)0250500750100005101520253099.1%
Method: RP-HPLC C18UV 220nmACN/H₂O + 0.1% TFA
CoA Included
HPLC Verified
GMP Compliant
Third-Party Tested
Same-Day Shipping
Batch Tracked

Specifications

Purity
≥99%
Form
Lyophilized Powder
CAS
159634-47-6
Mol. Weight
528.67 Da

How MK677 Works

MK-677 is an orally active, non-peptidic ghrelin receptor (GHSR-1a) agonist that mimics the GH-releasing activity of ghrelin. It stimulates pituitary GH release by binding to GHSR-1a, increasing GH pulse amplitude without altering pulse frequency. It also increases IGF-1 levels, promotes nitrogen retention, and stimulates appetite. Unlike peptide GH secretagogues, it is orally bioavailable and has a long duration of action, maintaining elevated GH and IGF-1 levels with once-daily dosing.

Research Applications

1
Oral GH secretagogue pharmacology
2
Muscle wasting and sarcopenia
3
Bone density improvement
4
Sleep quality and GH pulse enhancement
5
Age-related GH decline reversal

Pricing

SizePer Vial10-Pack
5mg
$50.00$500.00

10-pack pricing shown. Volume discounts for 50+ vials — contact us.

Certificate of Analysis

MiPeptidos
MK677
PASSES ALL SPECIFICATIONS
Batch NumberHR-MK67-2600315
Date of AnalysisJanuary 21, 2026
Purity (HPLC)99.1%
AppearanceWhite to off-white lyophilized powder
SolubilityFreely soluble in sterile water and bacteriostatic water
Molecular Weight (MS)528.67 Da — Confirmed
Endotoxin (LAL)<0.1 EU/mg
Sterility (USP <71>)Passes USP <71>

This COA is a representative sample. A batch-specific Certificate of Analysis with full HPLC chromatograms and mass spectrometry data is included with every order.

Research Use Only. This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.