MGF - Front - MiPeptidos
Growth Hormone / GH Secretagogues

MGF

CAS: Not formally assigned for the synthetic fragment

MGF is a research peptide in the growth hormone / gh secretagogues category. MGF is a splice variant of IGF-1 produced in mechanically stressed muscle tissue. MiPeptidos offers MGF in 1 sizes with 99.5% verified purity and full analytical documentation.

Starting at
$24.95/vial
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≥99% Purity
COA Included
Third-Party Tested
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CoA Included
HPLC Verified
GMP Compliant
Third-Party Tested
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How MGF Works

MGF is a splice variant of IGF-1 produced in mechanically stressed muscle tissue. Its unique E-domain (C-terminal peptide) activates satellite cells (muscle stem cells) and drives their proliferation while preventing premature differentiation. This is distinct from IGF-1Ea, which primarily drives differentiation. MGF also has neuroprotective properties and can protect cortical and hippocampal neurons. It acts through receptor-mediated signaling that is partially independent of the classical IGF-1 receptor.

Research Applications

1
Muscle satellite cell activation
2
Skeletal muscle repair and hypertrophy
3
Neuroprotection after ischemic events
4
Cardiac muscle repair
5
Age-related muscle wasting (sarcopenia)
View Published Research on PubMed →

Pricing

SizePer Vial10-Pack
2mg
$24.95$181.95

Prices shown per vial from 10-pack. Volume discounts available for 50+ vials — contact us.

HPLC Purity Analysis

High-Performance Liquid Chromatography
99.5%purity
mAURetention Time (min)0250500750100005101520253099.5%
Method: RP-HPLC C18 ColumnDetection: UV 220nmMobile Phase: Acetonitrile/Water + 0.1% TFA

Certificate of Analysis

MiPeptidos
MGF
PASSES ALL SPECIFICATIONS
Batch NumberHR-MGF-2600115
Date of AnalysisMarch 21, 2026
Purity (HPLC)99.5%
AppearanceWhite to off-white lyophilized powder
SolubilityFreely soluble in sterile water and bacteriostatic water
Molecular Weight (MS)~2867.16 Da — Confirmed
Endotoxin (LAL)<0.1 EU/mg
Sterility (USP <71>)Passes USP <71>

This COA is a representative sample. A batch-specific Certificate of Analysis with full HPLC chromatograms and mass spectrometry data is included with every MiPeptidos order.

Reconstitution Calculator

Add this much bacteriostatic water:
2.0 mL
2 mg MGF + 2.0 mL BAC water = 1 mg/mL

Inject bacteriostatic water slowly along the vial wall. Gently swirl until dissolved — never shake. Store reconstituted solution at 2-8°C and use within 30 days.

Download Product Brochure

Get our detailed MGF product brochure with specifications, research applications, HPLC analysis data, and reconstitution guide. Available in English and Spanish.

Customer Reviews

5.0/5from 1 review
Verified
Brian Kowalski·Pittsburgh, PA

Mechano Growth Factor from MiPeptidos is essential for our skeletal muscle satellite cell activation research. The IGF-1 splice variant peptide shows robust activity in our myoblast proliferation assays. Purity is verifi...

Feb 20, 2026
View All Reviews →

Frequently Asked Questions

MGF (CAS: Not formally assigned for the synthetic fragment) is a research compound, with a molecular weight of ~2867.16 Da in the Growth Hormone / GH Secretagogues category. MGF is a splice variant of IGF-1 produced in mechanically stressed muscle tissue. Its unique E-domain (C-terminal peptide) activates satellite cells (muscle stem cells) and drives their proliferation while preventing premature differentiation. Researchers commonly investigate MGF for Muscle satellite cell activation, Skeletal muscle repair and hypertrophy, Neuroprotection after ischemic events. Every vial from MiPeptidos includes batch-specific analytical documentation.
To reconstitute your MGF 2mg vial, let it reach room temperature for about 15-20 minutes out of the freezer. Slowly inject 1mL of bacteriostatic water along the inside wall of the vial — never aim directly at the peptide cake. Gently swirl until the powder fully dissolves; never shake, as this can denature the peptide. Store reconstituted MGF at 2-8°C and use within 30 days. MiPeptidos includes bacteriostatic water for purchase alongside all peptides.
MGF (Mechano-Growth Factor) is a 24-amino acid splice variant of IGF-1 that activates satellite cells for muscle repair, but it has a very short half-life of only minutes in circulation. PEG-MGF has a polyethylene glycol chain that extends this to hours, allowing systemic distribution. Non-PEGylated MGF is preferred for localized injection research where rapid, site-specific satellite cell activation is desired. MiPeptidos offers both forms for muscle regeneration studies.
Store lyophilized MGF at -20°C for maximum long-term stability — properly stored, it remains potent for 24+ months. Once reconstituted with bacteriostatic water, keep it refrigerated at 2-8°C and use within 30 days. In research applications, MGF has a reported half-life of ~5-7 minutes (very rapid degradation in serum), which informs dosing frequency and protocol design. Avoid repeated freeze-thaw cycles and protect from direct light. MiPeptidos ships every order with cold-chain packaging to maintain integrity during transit.
Every MGF order from MiPeptidos includes a batch-specific Certificate of Analysis. Our current batch (HR-MGF-2600115, tested March 21, 2026) shows 99.5% purity by HPLC, mass spectrometry confirmation at ~2867.16 Da, endotoxin levels below 0.1 EU/mg, and passing sterility per USP <71>. This level of documentation ensures you can verify compound identity and purity before beginning your research. MiPeptidos also offers bulk pricing on orders of 50+ vials — contact info@mipeptidos.com.

Specifications

Purity
≥99%
Form
Lyophilized Powder
CAS Number
Not formally assigned for the synthetic fragment
Mol. Weight
~2867.16 Da
Formula
C121H200N42O39
Half-Life
~5-7 minutes (very rapid degradation in serum)
Storage
Store at -20°C. Reconstituted: 2–8°C for up to 30 days.
Sizes
2mg

Sequence

24-amino acid E-domain peptide of the IGF-1Ec splice variant: YQPPSTNKNTKSQRRKGSTFEEHK

Research Use Only. This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.

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