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IGF-1 LR3 - Front - MiPeptidos
Growth Hormone / GH Secretagogues

IGF-1 LR3

CAS: 946870-92-4

muscle-signaling and hypertrophy beyond GH/IGF-1 axis · IGFBP-independent IGF-1 signaling · Cell proliferation and anti-apoptosis

IGF-1 LR3 is a synthetic 83-amino acid analog of IGF-1 (which has 70 amino acids) with an arginine at position 3 and a 13-amino acid extension at the N-terminus.

  • muscle-signaling and hypertrophy beyond GH/IGF-1 axis
  • IGFBP-independent IGF-1 signaling
  • Cell proliferation and anti-apoptosis
  • Glucose uptake and metabolic research
Research Use Only.

This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.

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≥99% Purity
COA Included
Third-Party Tested
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IGF-1 LR3 Brochure
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HPLC Purity Analysis

High-Performance Liquid Chromatography
99.5%purity
mAURetention Time (min)0250500750100005101520253099.5%
Method: RP-HPLC C18UV 220nmACN/H₂O + 0.1% TFA
CoA Included
HPLC Verified
GMP Compliant
Third-Party Tested
Same-Day Shipping
Batch Tracked

Specifications

Purity
≥99%
Form
Lyophilized Powder
CAS
946870-92-4
Mol. Weight
9117.50 Da

How IGF-1 LR3 Works

IGF-1 LR3 is a synthetic 83-amino acid analog of IGF-1 (which has 70 amino acids) with an arginine at position 3 and a 13-amino acid extension at the N-terminus. These modifications reduce binding to IGF binding proteins (IGFBPs) by over 100-fold, resulting in dramatically higher bioavailability and potency compared to native IGF-1. It activates the IGF-1 receptor to stimulate the PI3K/Akt and MAPK/ERK pathways, promoting cell proliferation, differentiation, survival, and protein synthesis in muscle and other tissues.

Research Applications

1
muscle-signaling and hypertrophy beyond GH/IGF-1 axis
2
IGFBP-independent IGF-1 signaling
3
Cell proliferation and anti-apoptosis
4
Glucose uptake and metabolic research
5
Tissue engineering and regenerative medicine

Pricing

SizePer Vial10-PackSavings
100mcgSale
$26.95$30.00
$269.5010% off
1mgBest ValueSale
$55.95$160.00
$559.5065% off

10-pack pricing shown. Volume discounts for 50+ vials — contact us.

Certificate of Analysis

MiPeptidos
IGF-1 LR3
PASSES ALL SPECIFICATIONS
Batch NumberHR-GF1L-2600115
Date of AnalysisMarch 5, 2026
Purity (HPLC)99.5%
AppearanceWhite to off-white lyophilized powder
SolubilityFreely soluble in sterile water and bacteriostatic water
Molecular Weight (MS)9117.50 Da — Confirmed
Endotoxin (LAL)<0.1 EU/mg
Sterility (USP <71>)Passes USP <71>

This COA is a representative sample. A batch-specific Certificate of Analysis with full HPLC chromatograms and mass spectrometry data is included with every order.

Research Use Only. This product is intended for laboratory research purposes only. Not for human consumption. Handle with appropriate safety precautions.