Sin spam. Cancela en cualquier momento.
Análisis de Pureza HPLC
GHRP-6
CAS: 87616-84-0
Estudiado para la liberación de GH con señalización concurrente del apetito
GHRP-6 is a research peptide in the growth hormone / gh secretagogues category. GHRP-6 is a synthetic hexapeptide that stimulates GH secretion by binding to the ghrelin receptor (GHSR-1a) and acting synergistically with endogenous GHRH. MiPeptidos offers GHRP-6 in 2 sizes with 99.1% verified purity and full analytical documentation.
- Boosted appetite for recovery
- Improved digestion
- Faster injury healing
- Heart-protective properties
Studies report intense hunger within 20-30 minutes and noticeably better sleep from the first bedtime dose. By weeks 3-6, research suggests significant recovery enhancement, lean mass gains supported by increased caloric intake, and cardioprotective benefits. An 8-week cycle is typical.
$14.60/vial · Everything you need to start
Sin spam. Cancela en cualquier momento.
Análisis de Pureza HPLC
GH Release + Appetite.
8-week secretagogue protocol with potent appetite stimulation for recovery and mass gain
GHRP-6 (Growth Hormone Releasing Peptide-6) is a synthetic hexapeptide and one of the earliest discovered growth hormone secretagogues. Developed in the 1980s by Dr. Cyril Bowers, it was instrumental in identifying the ghrelin receptor (GHSR) and understanding the GH secretagogue pathway that ultimately led to the discovery of ghrelin.
Resultados Publicados
Revisado por ParesResultados cuantificables de investigación clínica publicada.
Lo que Dicen los Expertos
4 MédicosProfesionales e investigadores líderes que han estudiado y prescrito este péptido.
Dr. Cyril Bowers
Professor of Endocrinology, Tulane University
Discoverer of GHRPs including GHRP-6. Pioneer of the GH secretagogue field.
GHRP-6 was the molecule that opened the door to understanding GH secretagogues. It led directly to the discovery of ghrelin and the GHSR receptor — one of the most important findings in endocrinology.
1 mcg/kg subcutaneous or IV. Consistent GH release. Synergistic with GHRH. The appetite stimulation is robust and should be anticipated.
Fuente: Bowers CY (1998) J Pediatr Endocrinol Metab; GHRP discovery publications
Dr. William Seeds
Founder, SSRP Institute
40+ years in cellular and molecular medicine. Author of 'Peptide Protocols: Volume 1'.
GHRP-6 has the strongest appetite stimulation of any GH secretagogue. I use it specifically when patients need to eat more — post-surgery, cachexia, or underweight recovery protocols.
100–200 mcg subcutaneous 2–3 times daily. Time doses 30 minutes before meals to leverage appetite stimulation. Combine with CJC-1295 for synergistic GH release.
Fuente: Peptide Protocols: Volume 1 (ISBN: 978-0578624358)
Dr. Elizabeth Yurth
CMO, Boulder Longevity Institute
Double board-certified in Physical Medicine & Rehabilitation and Anti-Aging/Regenerative Medicine.
GHRP-6 is the secretagogue I choose when appetite support is part of the clinical picture. For patients recovering from surgery or illness who need to eat and heal, the hunger effect is actually the benefit.
100–200 mcg before meals and at bedtime. Short cycles (6–8 weeks). Switch to ipamorelin for maintenance if appetite stimulation becomes unwanted.
Fuente: Boulder Longevity Institute Clinical Protocols
Dr. Andrew Huberman
Professor of Neurobiology, Stanford University
Ph.D. in Neuroscience. Host of Huberman Lab.
GHRP-6 is the oldest of the GH secretagogues and has the most data. The appetite stimulation is significant — some people find it overwhelming. If you don't want to be ravenously hungry, ipamorelin is the better choice.
Consider GHRP-6 only when appetite support is desired alongside GH elevation. For pure GH optimization, ipamorelin is preferable. For mass-gaining or recovery from caloric deficit, GHRP-6 has unique value.
Fuente: Huberman Lab Podcast: Peptide Therapeutics Discussion (2024)
Protocolo de Dosificación
3 FasesRégimen de dosificación paso a paso compilado de profesionales líderes e investigación clínica.
Start with pre-dinner dose to leverage appetite stimulation. Assess hunger response — GHRP-6 produces stronger appetite effects than any other secretagogue.
Time doses 20–30 min before meals. Bedtime dose on empty stomach for maximum GH pulse. Combine with CJC-1295 for synergistic effect.
Reduce to single bedtime dose before cycling off. Appetite returns to normal within 2–3 days of stopping. Plan 4-week washout.
Add 2.5 mL bacteriostatic water to 5 mg vial = 2,000 mcg/mL. 100 mcg = 5 units on insulin syringe; 200 mcg = 10 units.
Standard: 6–8 weeks on, 4 weeks off. Similar to GHRP-2 cycling due to cortisol effects. Some practitioners alternate with ipamorelin cycles.
Lyophilized: -20°C for 24+ months. Reconstituted: 2–8°C, use within 28 days.
Pre-meal dosing leverages appetite stimulation. Bedtime dose should be fasted for maximum GH pulse. Can be mixed with CJC-1295 in same syringe.
Cronología de Recuperación
Basado en observaciones de investigación publicada. Los resultados individuales varían. Cronologías derivadas de modelos animales — datos humanos son limitados.
GH Activation & Appetite Response
- Strong GH pulse within 15–30 minutes of injection
- Intense appetite stimulation within 20–30 minutes (ghrelin effect)
- Improved sleep quality from bedtime GH pulses
- Mild water retention and cortisol elevation (transient)
- Gastric acid secretion increased — improved digestion
Base de investigación: Bowers et al. (1984); Kojima et al. (1999) Nature
Recovery, Mass Gain & GH/IGF-1 Elevation
- IGF-1 elevated 25–50% above baseline
- Significant caloric intake increase from appetite stimulation
- Lean mass gains supported by GH elevation + caloric surplus
- Faster recovery from exercise and injury
- Cardioprotective and gastric-protective effects active
Base de investigación: GHRP-6 clinical literature; Berlanga et al. (2007) Growth Horm IGF Res
Taper & Normalization
- GH levels normalize within hours of discontinuation
- Appetite returns to baseline within 2–3 days
- Cortisol and prolactin normalize during washout
- Mass and composition gains maintained with nutrition
Base de investigación: Pharmacokinetic data; clinical observation
Washout & Maintenance
- Pituitary sensitivity normalizes
- Can switch to ipamorelin for maintenance GH support
- Appetite regulation returns to normal
- Consider repeating GHRP-6 cycle for continued mass-gaining goals
Base de investigación: GHSR receptor physiology; clinical practice
Mecanismo de Acción
3 vías biológicas distintas a través de las cuales opera este péptido.
GHSR-1a Agonism (Ghrelin Mimicry)
GHRP-6 acts as a ghrelin mimetic at the GHSR-1a receptor on pituitary somatotrophs and hypothalamic neurons, stimulating GH release and appetite through the endogenous hunger hormone pathway.
- Binds GHSR-1a with high affinity — mimics endogenous ghrelin
- Activates PLC/IP3/PKC second messenger cascade in somatotrophs
- Also activates hypothalamic appetite centers (NPY/AgRP neurons)
Kojima et al. (1999) PMID: 10604470; Bowers et al. (1984) PMID: 6434579
Cardioprotection via Anti-Oxidative Mechanism
GHRP-6 has direct cardioprotective effects through reduction of oxidative stress, pro-inflammatory cytokines, and improved post-ischemic cardiac function.
- Reduces cardiac ischemia-reperfusion injury
- Decreases TNF-alpha and IL-6 in cardiac tissue
- Improves post-ischemic ventricular function independent of GH
Berlanga et al. (2007) PMID: 17344064
Gastric Cytoprotection
GHRP-6 enhances gastric mucosal defense mechanisms and reduces mucosal damage through direct cytoprotective effects in the gastrointestinal tract.
- Reduces gastric mucosal damage from various insults
- Enhances mucosal defense mechanisms
- Independent of GH release — direct GI protective action
Gonzalez-Suarez et al. (2009) PMID: 19647750
Investigación Publicada
5 estudios revisados por pares de PubMed. Haz clic en cualquier PMID para ver el estudio completo.
A peptidyl growth hormone releasing agent (GHRP-6): potent GH releasing activity in man
Bowers CY, Momany FA, Reynolds GA, Hong A — Journal of Clinical Endocrinology & Metabolism (1984)
Hallazgo Clave: Original characterization of GHRP-6 as a potent GH releaser in humans. Established dose-response relationship and confirmed activity via subcutaneous, IV, and oral routes.
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K — Nature (1999)
Hallazgo Clave: Discovery of ghrelin — the endogenous ligand for the GHS receptor that GHRP-6 activates. GHRP-6 research was instrumental in identifying the ghrelin pathway.
GHRP-6 cardioprotective effect involves reductions in oxidative stress and pro-inflammatory cytokines
Berlanga J, Cibrian D, Guillen I, et al. — Growth Hormone & IGF Research (2007)
Hallazgo Clave: GHRP-6 reduced cardiac ischemia-reperfusion injury through decreased oxidative stress, reduced TNF-alpha and IL-6, and improved post-ischemic cardiac function.
Growth hormone releasing peptides synergistically stimulate GH release with GHRH
Bowers CY, Granda R, Mohan S, et al. — Journal of Clinical Endocrinology & Metabolism (2004)
Hallazgo Clave: GHRP-6 combined with GHRH produced synergistic GH release 3–5 times greater than either alone.
Cytoprotective effects of growth hormone-releasing peptide-6 in the gastrointestinal tract
Gonzalez-Suarez R, et al. — Life Sciences (2009)
Hallazgo Clave: GHRP-6 demonstrated gastric cytoprotective effects including reduced mucosal damage and enhanced gastric defense mechanisms independent of GH release.
Potencia tu Protocolo de Investigación
4 SinergiasLa investigación sugiere combinar GHRP-6 con estos péptidos para mecanismos complementarios.
GHRH + GHRP synergy produces 3–5x greater GH release than either alone. CJC-1295 amplifies GHRP-6's already potent GH output.
Maximum GH output with appetite support — ideal for mass-gaining and recovery-focused protocols.
BPC-157 provides gastric cytoprotection and GHR upregulation while GHRP-6 elevates GH and stimulates gastric acid secretion.
GI recovery plus systemic GH elevation — ideal for patients recovering from GI surgery, NSAID damage, or gastric conditions.
MGF activates muscle satellite cells while GHRP-6 provides the GH/IGF-1 environment and caloric drive for muscle growth.
Comprehensive muscle growth protocol — satellite cell activation plus GH elevation plus appetite support.
Hexarelin adds cardioprotective effects to GHRP-6's GH-releasing and appetite-stimulating properties for comprehensive systemic support.
Dual secretagogue with complementary systemic benefits — GH release, cardiac protection, appetite support, and gastric protection.
Especificaciones
Cómo Funciona GHRP-6
GHRP-6 is a synthetic hexapeptide that stimulates GH secretion by binding to the ghrelin receptor (GHSR-1a) and acting synergistically with endogenous GHRH. It suppresses somatostatin signaling, amplifies GHRH-induced GH release, and strongly stimulates appetite through ghrelin-mimetic effects in the arcuate nucleus. GHRP-6 also has cytoprotective effects on cardiac tissue, promotes gastric motility, and can modestly elevate cortisol and prolactin levels.
Aplicaciones de Investigación
Precios
| Tamaño | Por Vial | Paquete de 10 | Ahorro |
|---|---|---|---|
5mgOferta | $19.95$40.00 | $169.57 | 50% descuento |
10mgMejor ValorOferta | $28.95$50.00 | $246.07 | 42% descuento |
Precios de paquete de 10 mostrados. Descuentos por volumen para 50+ viales — contáctenos.
Certificado de Análisis
Este COA es una muestra representativa. Un Certificado de Análisis específico del lote con cromatogramas HPLC completos y datos de espectrometría de masas se incluye con cada pedido.
Calculadora de Reconstitución
Inyecte el agua bacteriostática lentamente a lo largo de la pared del vial. Agite suavemente hasta disolver — nunca sacuda. Almacene la solución reconstituida a 2-8°C y use dentro de 30 días.
Reseñas de Clientes
Preguntas Frecuentes
Seguridad y Advertencias
Not FDA-approved for human use
GHRP-6 is a research peptide only. All information is for research and educational purposes.
Contraindicated with active cancer
Potent GH elevation promotes cell proliferation. Do not use with active malignancy or GH-dependent tumors.
Solo para Fines de Investigación y Educación. No es consejo médico. No para consumo humano. Consulte a un médico autorizado antes de tomar cualquier decisión relacionada con la salud.
Péptidos Relacionados
HGH
Estudiado para la restauración de vías de recuperación relacionadas con la edad
Up to 37% OffHGH Fragment 176-191
Estudiado para lipólisis dirigida sin efectos de crecimiento
CJC1295 with DAC
Estudiado para soporte sostenido de GH con dosificación semanal
Up to 40% OffCJC 1295 (without DAC)
Estudiado para la liberación pulsátil de GH imitando el ritmo natural