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Análisis de Pureza HPLC
CJC 1295 5mg + IPA 5mg
El péptido estándar de oro estudiado para la optimización de GH
CJC 1295 5mg + IPA 5mg is a research-grade compound in the growth hormone / gh secretagogues category. It is widely used in laboratory settings for investigating its effects on biological systems. Available from MiPeptidos in 1 sizes, every batch is HPLC-verified at ≥99% purity with a full Certificate of Analysis included.
- 3-5x greater GH release
- Deeper sleep from night one
- Faster muscle recovery
- Clean energy all day
In weeks 1-2, studies report dramatically improved sleep quality within 3-5 days, often with vivid dreams indicating deeper slow-wave sleep. By weeks 3-6, research suggests markedly faster exercise recovery, improved skin hydration, and early body recomposition. Weeks 7-12 bring significant lean mass gains, visible fat reduction, and sustained cognitive clarity and vitality.
$29.20/vial · Everything you need to start
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Análisis de Pureza HPLC
Amplified GH Release.
The most prescribed GH secretagogue combination — dual-pathway synergy backed by clinical research
The CJC-1295 (without DAC) + Ipamorelin combination is widely regarded as the gold standard GH secretagogue protocol in peptide therapy. It pairs a GHRH analog (CJC-1295/Mod GRF 1-29) with a selective GHRP (Ipamorelin) to activate both sides of the GH release pathway simultaneously.
Resultados Publicados
Revisado por ParesResultados cuantificables de investigación clínica publicada.
Lo que Dicen los Expertos
4 MédicosProfesionales e investigadores líderes que han estudiado y prescrito este péptido.
Dr. William Seeds
Founder, SSRP Institute
40+ years in cellular and molecular medicine. Author of 'Peptide Protocols: Volume 1', the leading practitioner handbook for peptide therapy.
CJC-1295/Ipamorelin is my go-to combination for growth hormone optimization. The synergy is well-documented — you get a much larger GH pulse than either peptide alone, with an excellent safety profile.
100 mcg CJC-1295 + 200–300 mcg ipamorelin subcutaneous, 1–3 times daily. Bedtime dose most important. Always fasted. 8–12 week cycles.
Fuente: Peptide Protocols: Volume 1 (ISBN: 978-0578624358)
Dr. Elizabeth Yurth
CMO, Boulder Longevity Institute
Double board-certified in Physical Medicine & Rehabilitation and Anti-Aging/Regenerative Medicine. 30+ years in sports and spine orthopedics.
CJC/Ipamorelin is what I prescribe most frequently. It gives you a nice GH pulse at bedtime that mimics your natural physiology. Ipamorelin is the cleanest GHRP — no cortisol spike, no prolactin, no hunger.
Once daily at bedtime, subcutaneous. On an empty stomach. The combo vial is ideal for compliance — one reconstitution, one injection. Expect results by week 4–6.
Fuente: Wellness Mama Podcast Ep. 674; JJ Virgin Podcast Ep. 813
Dr. Rand McClain
Founder, Regenerative & Sports Medicine
Doctor of Osteopathy specializing in regenerative and sports medicine. One of the most prominent peptide therapy practitioners in Los Angeles.
The CJC/Ipa combination is essentially the gateway protocol for GH optimization. It's well-tolerated, effective, and the closest thing to physiological GH replacement without using actual HGH.
Nightly subcutaneous injection at bedtime, fasted. Can add a morning dose on training days. Monitor IGF-1 at baseline and 6 weeks. Target 200–300 ng/mL IGF-1 for most adults.
Fuente: Mark Bell's Power Project Podcast; Clinical practice protocols
Dr. Cyril Bowers
Professor of Endocrinology, Tulane University
Discoverer of growth hormone-releasing peptides (GHRPs). Pioneered the research on GHRH/GHRP synergy. Holder of multiple patents on GH secretagogues.
The combination of GHRH and GHRPs produces a synergistic release of GH that is significantly greater than either stimulus alone. This dual-pathway activation is the most effective way to stimulate endogenous GH secretion.
Combined GHRH + GHRP at physiological doses. The synergy is consistent and reproducible. GHRH provides the substrate signal; GHRP provides the amplifier.
Fuente: Bowers CY (2004) J Clin Endocrinol Metab; Multiple patents and publications
Protocolo de Dosificación
3 FasesRégimen de dosificación paso a paso compilado de profesionales líderes e investigación clínica.
Start with bedtime dose only at lower ipamorelin to assess tolerance. Must be fasted — no food for 2+ hours prior. GH pulse peaks within 30 minutes.
Bedtime dose is most important. Morning fasted dose adds significant benefit. Post-workout dose optional on training days. Each dose produces a discrete GH pulse.
Return to single bedtime dose before cycling off. Short half-life allows rapid clearance. Plan 4-week break before next cycle.
Add 2 mL bacteriostatic water to 10mg (5+5) combo vial. Each 10 units on insulin syringe = 250 mcg CJC + 250 mcg Ipamorelin. Typical dose: 4–8 units per injection.
Standard: 8–12 weeks on, 4 weeks off. Some practitioners run 5 on / 2 off. Shorter cycles (6 weeks) for beginners. Can be used long-term with periodic breaks.
Lyophilized: -20°C for 24+ months. Reconstituted: 2–8°C, use within 28 days. Protect from light. Do not shake — swirl gently.
MUST be fasted — insulin suppresses GH release. Wait 30+ minutes after injection before eating. Subcutaneous, rotate injection sites. Can combine with BPC-157 in the same syringe if using separate vials.
Cronología de Recuperación
Basado en observaciones de investigación publicada. Los resultados individuales varían. Cronologías derivadas de modelos animales — datos humanos son limitados.
GH Pulse Activation & Sleep Enhancement
- Amplified GH pulse detected within 15–30 minutes of first injection
- Improved sleep quality and deeper sleep reported within 3–5 days
- Vivid dreams commonly reported (marker of enhanced deep sleep)
- Mild tingling in extremities (transient GH-mediated water flux)
- No appetite increase (ipamorelin's selective advantage over GHRP-6)
Base de investigación: Bowers et al. (2004) J Clin Endocrinol Metab; Raun et al. (1998) Eur J Endocrinol
Recovery Enhancement & Body Composition Shifts
- Markedly faster recovery from exercise and training
- IGF-1 levels elevated 30–60% above baseline
- Improved skin quality, hydration, and wound healing
- Early body composition changes — muscle fullness, subcutaneous fat reduction
- Enhanced energy levels and morning alertness
Base de investigación: Bowers et al. (2004); clinical peptide therapy observations
Peak Body Composition & Performance
- Significant lean mass gain and fat loss measurable by DEXA
- Peak exercise performance and recovery capacity
- Hair, skin, and nail quality improvements clearly visible
- Improved lipid panel and fasting glucose markers
- Sustained cognitive clarity and vitality
Base de investigación: Clinical peptide therapy outcomes; GH/IGF-1 axis literature
Maintenance & Transition
- GH levels normalize within hours of last dose (short half-life)
- Body composition and performance gains maintained with lifestyle
- No withdrawal effects — pituitary function preserved
- Pituitary sensitivity may actually be enhanced vs pre-cycle baseline
Base de investigación: GHRH/GHRP receptor physiology; pulsatile delivery literature
Mecanismo de Acción
4 vías biológicas distintas a través de las cuales opera este péptido.
Dual GHRH + GHRP Synergy
CJC-1295 activates GHRH receptors (cAMP/PKA pathway) while Ipamorelin activates ghrelin receptors (PLC/IP3/PKC pathway). The two second-messenger cascades converge intracellularly to produce synergistic GH release 3–5 times greater than either alone.
- GHRH-R activates Gs → adenylyl cyclase → cAMP → PKA
- GHSR activates Gq → PLC → IP3 + DAG → PKC
- Intracellular convergence amplifies GH gene transcription and secretory vesicle release
Bowers et al. (2004) PMID: 15126525; Veldhuis et al. (2005) PMID: 16014405
Ipamorelin Selectivity
Ipamorelin uniquely activates GH release without stimulating ACTH, cortisol, or prolactin — a selectivity not shared by GHRP-2, GHRP-6, or hexarelin.
- No significant ACTH or cortisol elevation at GH-releasing doses
- No prolactin increase — avoids gynecomastia and mood effects
- No appetite stimulation — unlike GHRP-6 which strongly increases hunger
Raun et al. (1998) PMID: 9916862
Pulsatile GH Pattern Preservation
The short half-lives of both CJC-1295 (no DAC) and Ipamorelin produce discrete 30–60 minute GH pulses that return to baseline, preserving the natural pulsatile pattern critical for receptor sensitivity.
- GH pulse peaks at 15–30 min post-injection
- Returns to baseline within 2 hours
- Somatostatin feedback preserved — no receptor desensitization
Jaffe et al. (1999) PMID: 10484781
Nocturnal GH Amplification
Bedtime dosing amplifies the endogenous nocturnal GH surge during slow-wave sleep — the most physiologically important GH secretory window for tissue repair and recovery.
- 70% of daily GH output occurs during Stage 3/4 NREM sleep
- Age-related GH decline parallels slow-wave sleep loss
- Bedtime CJC/Ipa amplifies this critical repair window
Van Cauter et al. (2000) PMID: 10944644
Investigación Publicada
6 estudios revisados por pares de PubMed. Haz clic en cualquier PMID para ver el estudio completo.
Growth hormone releasing peptides synergistically stimulate GH release with GHRH in normal volunteers
Bowers CY, Granda R, Mohan S, et al. — Journal of Clinical Endocrinology & Metabolism (2004)
Hallazgo Clave: Combined GHRH + GHRP produced GH release 3–5 times greater than either alone in healthy adults. Confirmed the synergistic dual-pathway amplification principle underlying the CJC/Ipa combination.
Ipamorelin, the first selective growth hormone secretagogue
Raun K, Hansen BS, Johansen NL, et al. — European Journal of Endocrinology (1998)
Hallazgo Clave: Ipamorelin released GH with a potency and efficacy comparable to GHRP-6 but did NOT release ACTH, cortisol, or prolactin. The first truly selective GH secretagogue identified.
Ipamorelin as a new growth-hormone releasing peptide
Anderson NM, Bowers CY, et al. — Growth Hormone & IGF Research (2001)
Hallazgo Clave: Ipamorelin maintained consistent GH release over 15 consecutive daily doses without desensitization or tachyphylaxis — unique among GHRPs.
Age-related changes in slow wave sleep and REM sleep and relationship with growth hormone and cortisol levels in healthy men
Van Cauter E, Leproult R, Plat L — JAMA (2000)
Hallazgo Clave: GH secretion declines 75% by midlife, in parallel with slow-wave sleep loss. Bedtime GH secretagogues address the most impactful window for GH-mediated recovery.
Effect of low-dose recombinant human GHRH on GH secretion in healthy elderly men
Corpas E, Harman SM, Pineyro MA, Roberson R, Blackman MR — Journal of Clinical Endocrinology & Metabolism (1992)
Hallazgo Clave: Bedtime GHRH administration for 14 nights doubled nocturnal GH secretion in elderly men without tachyphylaxis. Established the bedtime dosing paradigm.
Growth hormone-releasing peptide-2 infusion synergizes with a GHRH analog to augment GH secretion in men
Veldhuis JD, Iranmanesh A, Bowers CY — Journal of Clinical Endocrinology & Metabolism (2005)
Hallazgo Clave: GHRH + GHRP infusion amplified GH pulse mass by 7.5-fold in men, with an ensemble mechanism that enhances both pulse frequency and pulse amplitude.
Potencia tu Protocolo de Investigación
4 SinergiasLa investigación sugiere combinar CJC 1295 5mg + IPA 5mg con estos péptidos para mecanismos complementarios.
BPC-157 upregulates GH receptors at injury sites while CJC/Ipa provides elevated GH — more signal meeting more receptors at the exact tissues that need repair.
The practitioner's top choice for injury recovery — dramatically accelerated tissue repair through dual GH amplification.
CJC/Ipa elevates GH for lean mass preservation while Fragment 176-191 targets fat oxidation through a separate lipolytic mechanism.
True body recomposition — simultaneous lean mass support and targeted fat loss. Fragment administered fasted AM, CJC/Ipa at bedtime.
TB-500 provides systemic anti-inflammatory and cell migration support that complements CJC/Ipa's GH-driven tissue repair.
Comprehensive recovery from injury or surgery — local and systemic repair pathways activated simultaneously.
MK677 provides sustained GH support and IGF-1 elevation that fills the gaps between CJC/Ipa doses.
24-hour GH axis optimization — pulsatile CJC/Ipa plus sustained MK677 secretagogue for maximum IGF-1 output.
Especificaciones
Precios
| Tamaño | Por Vial | Paquete de 10 |
|---|---|---|
10mg (5mg+5mg) | $80.00 | $680.00 |
Precios de paquete de 10 mostrados. Descuentos por volumen para 50+ viales — contáctenos.
Certificado de Análisis
Este COA es una muestra representativa. Un Certificado de Análisis específico del lote con cromatogramas HPLC completos y datos de espectrometría de masas se incluye con cada pedido.
Calculadora de Reconstitución
Inyecte el agua bacteriostática lentamente a lo largo de la pared del vial. Agite suavemente hasta disolver — nunca sacuda. Almacene la solución reconstituida a 2-8°C y use dentro de 30 días.
Reseñas de Clientes
Preguntas Frecuentes
Seguridad y Advertencias
Not FDA-approved for human use
Neither CJC-1295 nor Ipamorelin are approved pharmaceuticals. Research peptides only. All information is for research and educational purposes.
Contraindicated with active cancer or tumors
GH/IGF-1 elevation promotes cell proliferation. Contraindicated with active malignancy, history of GH-dependent tumors, or unmonitored elevated IGF-1.
Solo para Fines de Investigación y Educación. No es consejo médico. No para consumo humano. Consulte a un médico autorizado antes de tomar cualquier decisión relacionada con la salud.
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